Endothelial heparan sulfate 6-O-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor.
about
Glycoconjugates and related molecules in human vascular endothelial cellsFell-Muir Lecture: Heparan sulphate and the art of cell regulation: a polymer chain conducts the protein orchestra.Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signalingSpatio-temporally precise activation of engineered receptor tyrosine kinases by light.Modular synthesis of heparin-related tetra-, hexa- and octasaccharides with differential o-6 protections: programming for regiodefined 6-o-modifications.A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3)Synthetic Site-Selectively Mono-6-O-Sulfated Heparan Sulfate Dodecasaccharide Shows Anti-Angiogenic Properties In Vitro and Sensitizes Tumors to Cisplatin In Vivo.Synthetic heparan sulfate dodecasaccharides reveal single sulfation site interconverts CXCL8 and CXCL12 chemokine biology.Xanthatin, a novel potent inhibitor of VEGFR2 signaling, inhibits angiogenesis and tumor growth in breast cancer cells.Heparanase and Syndecan-4 Are Involved in Low Molecular Weight Fucoidan-Induced Angiogenesis.The role of Drosophila heparan sulfate 6-O-endosulfatase in sulfation compensation.Formononetin, a novel FGFR2 inhibitor, potently inhibits angiogenesis and tumor growth in preclinical models.Proteoglycans and their roles in brain cancer.Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analogue reduces angiogenesisHeparan sulfate in angiogenesis: a target for therapy.The "in and out" of glucosamine 6-O-sulfation: the 6th sense of heparan sulfate.Integrated Approach to Identify Heparan Sulfate Ligand Requirements of Robo1.Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases.The potential of fibroblast growth factor/fibroblast growth factor receptor signaling as a therapeutic target in tumor angiogenesis.Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1 (HS3ST3B1) promotes angiogenesis and proliferation by induction of VEGF in acute myeloid leukemia cells.Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease.Segregation of late outgrowth endothelial cells into functional endothelial CD34- and progenitor-like CD34+ cell populations.2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration.Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase
P2860
Q27008374-F7CB0E94-908B-49C1-B217-DBEAB5766104Q30568524-EF21114D-3E48-4C83-A667-DEA385858F9EQ33675726-05A70477-7433-4F18-90EF-88F0C6FE9AE3Q34324550-67DB8989-3B27-448B-A717-9C21FA63512BQ35574973-FCE851E7-605B-41CF-B0E3-69323616157EQ35774804-621223AD-1CBC-4A97-A752-B57000655A24Q36094711-71D90C14-54CD-4798-B8CA-5FB1C3966A16Q36169514-A279B679-BBF2-428B-806C-3BB14B8DCB95Q36261367-AE84E5FA-CFCD-42CF-9874-003ABF0A75B4Q36329663-EDA0C9E0-71A4-4983-A5F6-8F65287B5A86Q36647389-3FC7C95D-656E-46F5-9906-3CCB3B455182Q36689042-C0DB7461-17D1-4BF1-A6B3-8910FA525611Q36816444-94F7AD9B-EC6C-497C-9EB6-7E50C2E2C9CDQ37291115-A55571D9-59A9-4DAA-8DE9-8B40C03684F3Q38154506-01E8C607-C40B-4069-B838-AB8D199DBA77Q38290246-2C80042F-E02A-4E98-91E0-ABC81D2637D5Q38290964-088C2911-BFD5-4A10-AB9A-7FEC64C9754EQ38406589-3E7387E5-0D7F-4CA8-A65F-BCD943900C01Q38540713-BC9A1FEA-106B-4BD1-AD9D-75B73F032655Q38925857-426F4BBF-DA4A-4CFF-AAB4-12021DB16DDDQ39120713-92A5CB9E-FA8F-4C2C-A505-05009D6C2BA7Q40225619-E605E989-3320-46C7-B32D-32A368275076Q41873669-EF6051D9-6C6F-41D5-B561-C47FDEA3B0D2Q55279885-D1FE7463-2BBF-4043-9733-CFBBC45AA7ADQ56395838-E9323CBE-933E-4872-9BCC-7913A3D602E8
P2860
Endothelial heparan sulfate 6-O-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Endothelial heparan sulfate 6- ...... lar endothelial growth factor.
@ast
Endothelial heparan sulfate 6- ...... lar endothelial growth factor.
@en
type
label
Endothelial heparan sulfate 6- ...... lar endothelial growth factor.
@ast
Endothelial heparan sulfate 6- ...... lar endothelial growth factor.
@en
prefLabel
Endothelial heparan sulfate 6- ...... lar endothelial growth factor.
@ast
Endothelial heparan sulfate 6- ...... lar endothelial growth factor.
@en
P2093
P2860
P356
P1476
Endothelial heparan sulfate 6- ...... ular endothelial growth factor
@en
P2093
Claire L Cole
Cristina Ferreras
Egle Avizienyte
Graham Rushton
John M Gardiner
Kaye J Williams
Muhammad Babur
Toin H van Kuppevelt
P2860
P304
36132-36146
P356
10.1074/JBC.M112.384875
P407
P577
2012-08-27T00:00:00Z