Nanog signaling in cancer promotes stem-like phenotype and immune evasion
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Induction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotubesThe Role of microRNAs in Stemness of Cancer Stem CellsTherapeutic targeting of replicative immortalityStem Cell-Derived Extracellular Vesicles and Immune-ModulationMicroRNAs targeting prostate cancer stem cellsHypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to HypoxiaConcise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding QuestionsDownregulation of ERp57 expression is associated with poor prognosis in early-stage cervical cancerCauses of genome instability: the effect of low dose chemical exposures in modern societyNanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W speciesBlockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cellsSustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markersEmerging role of nanog in tumorigenesis and cancer stem cells.RepSox slows decay of CD34+ acute myeloid leukemia cells and decreases T cell immunoglobulin mucin-3 expressionCo-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinomaCombined stimulation of IL-2 and 4-1BB receptors augments the antitumor activity of E7 DNA vaccines by increasing Ag-specific CTL responses.A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumorsAPI5 confers tumoral immune escape through FGF2-dependent cell survival pathway.High glutathione and glutathione peroxidase-2 levels mediate cell-type-specific DNA damage protection in human induced pluripotent stem cellsThe role of Nanog expression in tamoxifen-resistant breast cancer cellsClinical significance of OCT4 and SOX2 protein expression in cervical cancer.A candidate Chinese medicine preparation-Fructus Viticis Total Flavonoids inhibits stem-like characteristics of lung cancer stem-like cellsTargeting stemness is an effective strategy to control EML4-ALK+ non-small cell lung cancer cells.Whole-transcriptome analysis of flow-sorted cervical cancer samples reveals that B cell expressed TCL1A is correlated with improved survival.Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo.Targeting IκB Kinase β/NF-κB Signaling in Human Prostate Cancer by a Novel IκB Kinase β Inhibitor CmpdA.Targeting cancer stem cells: emerging role of Nanog transcription factorIn vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals.miR-150 Suppresses the Proliferation and Tumorigenicity of Leukemia Stem Cells by Targeting the Nanog Signaling Pathway.API5 confers cancer stem cell-like properties through the FGF2-NANOG axis.Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression.REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survivalCellular and molecular mechanisms in cancer immune escape: a comprehensive review.ZNF281/ZBP-99: a new player in epithelial-mesenchymal transition, stemness, and cancer.Using induced pluripotent stem cells as a tool for modelling carcinogenesis.Stem cell transcription factor NANOG in cancers--is eternal youth a curse?Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter.Leukemia inhibitory factor protects cholangiocarcinoma cells from drug-induced apoptosis via a PI3K/AKT-dependent Mcl-1 activation.Inhibition of NANOG/NANOGP8 downregulates MCL-1 in colorectal cancer cells and enhances the therapeutic efficacy of BH3 mimeticsAcquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance.
P2860
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P2860
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
@ast
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
@en
type
label
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
@ast
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
@en
prefLabel
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
@ast
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
@en
P2093
P2860
P50
P356
P1476
Nanog signaling in cancer promotes stem-like phenotype and immune evasion
@en
P2093
Bo Wook Kim
Chih-Ping Mao
Jae-Hoon Kim
Jin Hee Kim
Kwon-Ho Song
Kyung Hee Noh
Tae Woo Kim
Young-Ho Lee
P2860
P304
P356
10.1172/JCI64057
P407
P577
2012-10-24T00:00:00Z