The membrane attack mechanism of complement: the three polypeptide chain structure of the eigth component (C8)
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Molecular organization of C9 within the membrane attack complex of complement. Induction of circular C9 polymerization by the C5b-8 assemblyTwo types of dysfunctional eighth component of complement (C8) molecules in C8 deficiency in man. Reconstitution of normal C8 from the mixture of two abnormal C8 molecules.Molecular weight of the membrane C5b-9 complex of human complement: characterization of the terminal complex as a C5b-9 monomer.Membrane attack complex of complement: distribution of subunits between the hydrocarbon phase of target membranes and water.Killing of human melanoma cells by the membrane attack complex of human complement as a function of its molecular composition.Antigenic crossreactivity of the alpha subunit of complement component C8 with the cysteine-rich domain shared by complement component C9 and low density lipoprotein receptor.Polymerization of the ninth component of complement (C9): formation of poly(C9) with a tubular ultrastructure resembling the membrane attack complex of complement.Ultrastructure of the membrane attack complex of complement: detection of the tetramolecular C9-polymerizing complex C5b-8.Bactericidal activity of the alternative complement pathway generated from 11 isolated plasma proteins.Occurrence of an incomplete C8 molecule in homozygous C8 deficiency in manAssembly of the functional membrane attack complex of human complement: formation of disulfide-linked C9 dimers.Molecular cloning of Limulus alpha 2-macroglobulin.Genetic polymorphism in C8 beta-chains. Evidence for two unlinked genetic loci for the eighth component of human complement (C8)Absence of the eighth component of complement in association with systemic lupus erythematosus-like disease.Membrane attack complex of complement: generation of high-affinity phospholipid binding sites by fusion of five hydrophilic plasma proteins.Molecular reorganization of lipid bilayers by complement: a possible mechanism for membranolysisIsolation of a human erythrocyte membrane protein capable of inhibiting expression of homologous complement transmembrane channels.Induction of expression of cell-surface homologous restriction factor upon anti-CD3 stimulation of human peripheral lymphocytes.Inherited deficiencies of complement in man.Human C81 (alpha-gamma) polymorphism: detection in the alpha-gamma subunit on SDS-PAGE, formal genetics and linkage relationship.The pore-forming protein (perforin) of cytolytic T lymphocytes is immunologically related to the components of membrane attack complex of complement through cysteine-rich domainsMembrane attack complex of complement: a structural analysis of its assembly.Lysis of measles virus-infected cells by the purified cytolytic alternative complement pathway and antibody.Assembly of the cytolytic alternative pathway of complement from 11 isolated plasma proteins.C5b-9 dimer: isolation from complement lysed cells and ultrastructural identification with complement-dependent membrane lesions.Inherited C8 beta subunit deficiency in a patient with recurrent meningococcal infections: in vivo functional kinetic analysis of C8.Glycyrrhizin inhibits the lytic pathway of complement--possible mechanism of its anti-inflammatory effect on liver cells in viral hepatitis.Interaction of the eighth component of guinea pig complement (C8) with the membrane-bound C5b-7 complex. The binding site of C8 to C5b-7 is formed on association of the alpha-gamma subunit with the beta-chain.Human complement component C8
P2860
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P2860
The membrane attack mechanism of complement: the three polypeptide chain structure of the eigth component (C8)
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1976 nî lūn-bûn
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1976年学术文章
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The membrane attack mechanism ...... re of the eigth component (C8)
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The membrane attack mechanism ...... re of the eigth component (C8)
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type
label
The membrane attack mechanism ...... re of the eigth component (C8)
@ast
The membrane attack mechanism ...... re of the eigth component (C8)
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prefLabel
The membrane attack mechanism ...... re of the eigth component (C8)
@ast
The membrane attack mechanism ...... re of the eigth component (C8)
@en
P2860
P356
P1476
The membrane attack mechanism ...... re of the eigth component (C8)
@en
P2093
Müller-Eberhard HJ
P2860
The membrane attack mechanism of complement. Isolation and subunit composition of the C5b-9 complex.
The eighth component of human complement (C8): isolation, characterization, and hemolytic efficiency
P304
P356
10.1084/JEM.143.5.1131
P407
P577
1976-05-01T00:00:00Z