Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors
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IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesisThe molecular mechanism of osteoclastogenesis in rheumatoid arthritisImmune regulation of osteoclast function in postmenopausal osteoporosis: a critical interdisciplinary perspectiveIL-6 and IGF-1 Signaling Within and Between Muscle and Bone: How Important is the mTOR Pathway for Bone Metabolism?Multiple organ dysfunction and systemic inflammation after spinal cord injury: a complex relationshipCiliary neurotrophic factor inhibits bone formation and plays a sex-specific role in bone growth and remodelingInterleukin-1beta-induced promatrilysin expression is mediated by NFkappaB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaPCommitment and differentiation of stem cells to the osteoclast lineage.Global gene expression analysis of the interaction between cancer cells and osteoblasts to predict bone metastasis in breast cancerThe therapeutic potential of interleukin-6 hyperagonists and antagonists.Interleukin-6 and new strategies for the treatment of cancer, hyperproliferative diseases and paraneoplastic syndromes.Regulatory mechanisms of osteoblast and osteoclast differentiation.Bone density and hyperlipidemia: the T-lymphocyte connection.Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells.Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways.Comparison of the roles of IL-1, IL-6, and TNFalpha in cell culture and murine models of aseptic loosening.The role of osteoblast cells in the pathogenesis of unicameral bone cysts.Derivation of a novel undifferentiated human foetal phenotype in serum-free cultures with BMP-2.Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis.Peri-implant crestal bone loss: a putative mechanism.Activin-βC modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways.The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.The role of gp130-mediated signals in osteoclast development: regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures.Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formationStromal-Initiated Changes in the Bone Promote Metastatic Niche Development.Interleukin-6 in aging and chronic disease: a magnificent pathwayNovel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor.Il-6 signaling in inflammatory bowel disease: pathophysiological role and clinical relevance.Contributions to osteoclast biology from Japan.ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease.Sarilumab plus methotrexate suppresses circulating biomarkers of bone resorption and synovial damage in patients with rheumatoid arthritis and inadequate response to methotrexate: a biomarker study of MOBILITYTransgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency.Generation of a transgenic mouse line for conditional expression of human IL-6.A novel distal enhancer mediates cytokine induction of mouse RANKl gene expression.Combination of IL-6 and sIL-6R differentially regulate varying levels of RANKL-induced osteoclastogenesis through NF-κB, ERK and JNK signaling pathways.Interaction of staphylococci with bone.Effects of inflammatory and anti-inflammatory cytokines on the bone.The membrane proximal cytokine receptor domain of the human interleukin-6 receptor is sufficient for ligand binding but not for gp130 association.Interleukin-6 and its soluble receptor cause a marked induction of collagenase 3 expression in rat osteoblast cultures.
P2860
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P2860
Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Interleukin (IL)-6 induction o ...... not on osteoclast progenitors
@ast
Interleukin (IL)-6 induction o ...... not on osteoclast progenitors
@en
type
label
Interleukin (IL)-6 induction o ...... not on osteoclast progenitors
@ast
Interleukin (IL)-6 induction o ...... not on osteoclast progenitors
@en
prefLabel
Interleukin (IL)-6 induction o ...... not on osteoclast progenitors
@ast
Interleukin (IL)-6 induction o ...... not on osteoclast progenitors
@en
P2093
P2860
P356
P1476
Interleukin (IL)-6 induction o ...... not on osteoclast progenitors
@en
P2093
Findlay DM
Katagiri T
Kishimoto T
Takahashi N
P2860
P304
P356
10.1084/JEM.182.5.1461
P407
P577
1995-11-01T00:00:00Z