Disruption of transforming growth factor beta signaling by a novel ligand-dependent mechanism
about
Targeting TGF-β signaling in cancerTargeting the Transforming Growth Factor-β Signaling in Cancer TherapyTGF-β - an excellent servant but a bad masterThe type III transforming growth factor-β receptor inhibits proliferation, migration, and adhesion in human myeloma cells.Transient inhibition of transforming growth factor-beta1 in human diabetic CD34+ cells enhances vascular reparative functions.Neoplastic development in plasma cells.Role of transforming growth factor-beta in hematologic malignanciesActivation of TGF-beta within cultured hepatocytes and in liver injury leads to intracrine signaling with expression of connective tissue growth factor.Fibroblast growth factor receptor 3 interacts with and activates TGFβ-activated kinase 1 tyrosine phosphorylation and NFκB signaling in multiple myeloma and bladder cancer.Transforming growth factor-beta 1 mutations in Camurati-Engelmann disease lead to increased signaling by altering either activation or secretion of the mutant protein.p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation.Minimal effects on immune parameters following chronic anti-TGF-beta monoclonal antibody administration to normal mice.
P2860
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P2860
Disruption of transforming growth factor beta signaling by a novel ligand-dependent mechanism
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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name
Disruption of transforming gro ...... vel ligand-dependent mechanism
@ast
Disruption of transforming gro ...... vel ligand-dependent mechanism
@en
type
label
Disruption of transforming gro ...... vel ligand-dependent mechanism
@ast
Disruption of transforming gro ...... vel ligand-dependent mechanism
@en
prefLabel
Disruption of transforming gro ...... vel ligand-dependent mechanism
@ast
Disruption of transforming gro ...... vel ligand-dependent mechanism
@en
P2093
P2860
P356
P1476
Disruption of transforming gro ...... vel ligand-dependent mechanism
@en
P2093
Alexander Kovalchuk
Gary M Jones
John J Letterio
Michael Potter
Seong-Jin Kim
Shellyann Sharpe
Stephanie Amoroso
Tania Fernandez
Valery Bliskovski
P2860
P304
P356
10.1084/JEM.20011521
P407
P577
2002-05-01T00:00:00Z