Human genome-wide association and mouse knockout approaches identify platelet supervillin as an inhibitor of thrombus formation under shear stress
about
A genome-wide association study meta-analysis of clinical fracture in 10,012 African American womenPhosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin.The complex transcriptional landscape of the anucleate human platelet.Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle.An N-terminal, 830 residues intrinsically disordered region of the cytoskeleton-regulatory protein supervillin contains Myosin II- and F-actin-binding sites.Supervillin-mediated suppression of p53 protein enhances cell survival.Genomic architecture of sickle cell disease in West African children.Gelsolin: the tail of a molecular gymnast.Replication and hematological characterization of human platelet reactivity genetic associations in men from the Caerphilly Prospective Study (CaPS).Supervillin binds the Rac/Rho-GEF Trio and increases Trio-mediated Rac1 activation.The pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants.
P2860
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P2860
Human genome-wide association and mouse knockout approaches identify platelet supervillin as an inhibitor of thrombus formation under shear stress
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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name
Human genome-wide association ...... s formation under shear stress
@ast
Human genome-wide association ...... s formation under shear stress
@en
type
label
Human genome-wide association ...... s formation under shear stress
@ast
Human genome-wide association ...... s formation under shear stress
@en
prefLabel
Human genome-wide association ...... s formation under shear stress
@ast
Human genome-wide association ...... s formation under shear stress
@en
P2093
P2860
P50
P1433
P1476
Human genome-wide association ...... s formation under shear stress
@en
P2093
Altaf Kondkar
Daniel Covarrubias
Elizabeth J Luna
Ian B Gibson
Molly Bray
Moritz Stolla
Nacima Hadjout-Rabi
Paul F Bray
Srikanth Nagalla
Stephen N Jones
P2860
P304
P356
10.1161/CIRCULATIONAHA.112.091462
P407
P577
2012-05-01T00:00:00Z