Wnt1 inducible signaling pathway protein 1 (WISP1) targets PRAS40 to govern β-amyloid apoptotic injury of microglia. - sprookjes - yvandenbroek - TriplyDB

Wnt1 inducible signaling pathway protein 1 (WISP1) targets PRAS40 to govern β-amyloid apoptotic injury of microglia.

Wnt1 inducible signaling pathway protein 1 (WISP1) targets PRAS40 to govern β-amyloid apoptotic injury of microglia.

http://www.wikidata.org/entity/Q36465550

about

Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR Stem cell guidance through the mechanistic target of rapamycin Cutting through the complexities of mTOR for the treatment of stroke Driving neural regeneration through the mammalian target of rapamycin Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy New Insights for Oxidative Stress and Diabetes Mellitus Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease WISP1: Clinical insights for a proliferative and restorative member of the CCN family Taking aim at Alzheimer's disease through the mammalian target of rapamycin Regeneration in the nervous system with erythropoietin A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade Novel directions for diabetes mellitus drug discovery Picking a bone with WISP1 (CCN4): new strategies against degenerative joint disease Tuberous sclerosis protein 2 (TSC2) modulates CCN4 cytoprotection during apoptotic amyloid toxicity in microglia.WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1 Acute Simian Varicella Virus Infection Causes Robust and Sustained Changes in Gene Expression in the Sensory Ganglia.Programming apoptosis and autophagy with novel approaches for diabetes mellitus.Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders.Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer.mTOR Signaling in Parkinson's Disease.Warming Up to New Possibilities with the Capsaicin Receptor TRPV1: mTOR, AMPK, and Erythropoietin.Therapeutic targets for cancer: current concepts with PI 3-K, Akt, & mTOR.Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors.The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disorders.Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling.

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P2860

Wnt1 inducible signaling pathway protein 1 (WISP1) targets PRAS40 to govern β-amyloid apoptotic injury of microglia.

http://www.wikidata.org/entity/Q36465550

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Wnt1 inducible signaling pathw ...... apoptotic injury of microglia.

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Wnt1 inducible signaling pathw ...... apoptotic injury of microglia.

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type

label

Wnt1 inducible signaling pathw ...... apoptotic injury of microglia.

@ast

Wnt1 inducible signaling pathw ...... apoptotic injury of microglia.

@en

prefLabel

Wnt1 inducible signaling pathw ...... apoptotic injury of microglia.

@ast

Wnt1 inducible signaling pathw ...... apoptotic injury of microglia.

@en

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Current neurovascular research

P1476

Wnt1 inducible signaling pathw ...... apoptotic injury of microglia.

@en

P2093

Kenneth Maiese

http://www.w3.org/2001/XMLSchema#string

Shaohui Wang

http://www.w3.org/2001/XMLSchema#string

Yan Chen Shang

http://www.w3.org/2001/XMLSchema#string

Zhao Zhong Chong

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death

Rapamycin and mTOR kinase inhibitors

WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase

Interleukin-18/WNT1-inducible signaling pathway protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation

mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease

PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding

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239-249

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10.2174/156720212803530618

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4

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9

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2012-11-01T00:00:00Z

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230636753

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22873724

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apoptotic process

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3521866

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