Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis - sprookjes - yvandenbroek - TriplyDB

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

http://www.wikidata.org/entity/Q36498218

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Recent Insights into Cell Surface Heparan Sulphate Proteoglycans and Cancer Mechanisms of heparanase inhibitors in cancer therapy.Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data.Heparanase 2 Attenuates Head and Neck Tumor Vascularity and Growth.Heparanase is required for activation and function of macrophages.The prognostic significance of heparanase expression in metastatic melanoma NK cell heparanase controls tumor invasion and immune surveillance.Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease.Heparanase and cancer progression: New directions, new promises.Chemotherapy induces expression and release of heparanase leading to changes associated with an aggressive tumor phenotype.Gemcitabine-induced heparanase promotes aggressiveness of pancreatic cancer cells via activating EGFR signaling.Heparanase: From basic research to therapeutic applications in cancer and inflammation.Opposing Functions of Heparanase-1 and Heparanase-2 in Cancer Progression.Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior.Microenvironment modulation and enhancement of antilymphoma therapy by the heparanase inhibitor roneparstat.Prognostic significance of heparanase expression in primary and metastatic breast carcinoma.Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer.Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors.Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression

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P2860

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

http://www.wikidata.org/entity/Q36498218

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

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name

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

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Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

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type

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Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

@ast

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

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prefLabel

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

@ast

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

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PNAS.1519453113

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

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P2093

Edward Hammond

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Gil Arvatz

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Inna Naroditsky

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Israel Vlodavsky

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Marina Weissmann

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Mary Ng

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Neta Ilan

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Netanel Horowitz

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Sari Feld

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Yi Zhang

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P2860

Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans

Processing and activation of latent heparanase occurs in lysosomes

Prodding the Beast: Assessing the Impact of Treatment-Induced Metastasis

Pathophysiology of heparan sulphate: many diseases, few drugs

The tumor microenvironment shapes hallmarks of mature B-cell malignancies.

Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate

Inhibition of heparanase-mediated degradation of extracellular matrix heparan sulfate by non-anticoagulant heparin species

Accessories to the crime: functions of cells recruited to the tumor microenvironment

Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling.

Heparanase: a key enzyme involved in cell invasion.

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704-709

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