RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae
about
Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cellsSaccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptorGerminating fission yeast spores delay in G1 in response to UV irradiationRepair on the go: E. coli maintains a high proliferation rate while repairing a chronic DNA double-strand breakRfc5, in cooperation with rad24, controls DNA damage checkpoints throughout the cell cycle in Saccharomyces cerevisiae.A morphogenesis checkpoint monitors the actin cytoskeleton in yeastNORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae.The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae.A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activationMec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathwayThe SFP1 gene product of Saccharomyces cerevisiae regulates G2/M transitions during the mitotic cell cycle and DNA-damage responseThe checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeastThe Saccharomyces cerevisiae RAD9, RAD17, RAD24 and MEC3 genes are required for tolerating irreparable, ultraviolet-induced DNA damage.A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutantsThe RAD6/BRE1 histone modification pathway in Saccharomyces confers radiation resistance through a RAD51-dependent process that is independent of RAD18RAD53 regulates DBF4 independently of checkpoint function in Saccharomyces cerevisiaeInvolvement of the PP2C-like phosphatase Ptc2p in the DNA checkpoint pathways of Saccharomyces cerevisiae.A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription.Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism.Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombinationRB-dependent S-phase response to DNA damageA p53-independent damage-sensing mechanism that functions as a checkpoint at the G1/S transition in Chinese hamster ovary cells.Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiaeHistone H3 K79 methylation states play distinct roles in UV-induced sister chromatid exchange and cell cycle checkpoint arrest in Saccharomyces cerevisiae.The Saccharomyces cerevisiae RAD9 checkpoint reduces the DNA damage-associated stimulation of directed translocations.Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast.DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpointsA role for the umuDC gene products of Escherichia coli in increasing resistance to DNA damage in stationary phase by inhibiting the transition to exponential growthDynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activityTopBP1 functions with 53BP1 in the G1 DNA damage checkpoint.Distribution and dynamics of chromatin modification induced by a defined DNA double-strand breakRad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing conditions in S. cerevisiaeEffects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cellsTelomere loss in somatic cells of Drosophila causes cell cycle arrest and apoptosis.
P2860
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P2860
RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
RAD9-dependent G1 arrest defin ...... le of Saccharomyces cerevisiae
@ast
RAD9-dependent G1 arrest defin ...... le of Saccharomyces cerevisiae
@en
type
label
RAD9-dependent G1 arrest defin ...... le of Saccharomyces cerevisiae
@ast
RAD9-dependent G1 arrest defin ...... le of Saccharomyces cerevisiae
@en
prefLabel
RAD9-dependent G1 arrest defin ...... le of Saccharomyces cerevisiae
@ast
RAD9-dependent G1 arrest defin ...... le of Saccharomyces cerevisiae
@en
P2093
P2860
P356
P1476
RAD9-dependent G1 arrest defin ...... le of Saccharomyces cerevisiae
@en
P2093
A S Friedberg
E C Friedberg
P2860
P304
P356
10.1073/PNAS.90.17.7985
P407
P577
1993-09-01T00:00:00Z