Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models
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Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?Attenuation of noise-induced hearing loss using methylene blue.Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypesPreventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.Proteasome-mediated proteolysis of the polyglutamine-expanded androgen receptor is a late event in spinal and bulbar muscular atrophy (SBMA) pathogenesis.Alleviating neurodegeneration in Drosophila models of PolyQ diseases.TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells.Reversing the Warburg effect as a treatment for glioblastoma.Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's diseaseAlternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots.Aggregation formation in the polyglutamine diseases: protection at a cost?TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's diseaseSUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation.Experimental models for identifying modifiers of polyglutamine-induced aggregation and neurodegeneration.Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins.Potential therapeutic targets in polyglutamine-mediated diseases.Studying polyglutamine diseases in Drosophila.Shedding Light on Alzheimer's β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates.Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.Nanoparticulate strategies for the treatment of polyglutamine diseases by halting the protein aggregation process.Methylene Blue Partially Rescues Heart Defects in a Drosophila Model of Huntington's Disease.Methylene Blue Attenuates iNOS Induction Through Suppression of Transcriptional Factor Binding Amid iNOS mRNA Transcription.RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.Tau aggregation inhibitors: the future of Alzheimer's pharmacotherapy?Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.Fractionation for Resolution of Soluble and Insoluble Huntingtin Species.Pharmacological Agents Targeting the Cellular Prion Protein.
P2860
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P2860
Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Methylene blue modulates hunti ...... in Huntington's disease models
@ast
Methylene blue modulates hunti ...... in Huntington's disease models
@en
type
label
Methylene blue modulates hunti ...... in Huntington's disease models
@ast
Methylene blue modulates hunti ...... in Huntington's disease models
@en
prefLabel
Methylene blue modulates hunti ...... in Huntington's disease models
@ast
Methylene blue modulates hunti ...... in Huntington's disease models
@en
P2093
P2860
P1476
Methylene blue modulates hunti ...... in Huntington's disease models
@en
P2093
Andrew Tran
Charles Glabe
Emily Mitchell Sontag
Gregor P Lotz
Guocheng Yang
J Lawrence Marsh
Leslie M Thompson
Mihaela Necula
Namita Agrawal
P2860
P304
11109-11119
P356
10.1523/JNEUROSCI.0895-12.2012
P407
P577
2012-08-01T00:00:00Z