Spontaneous transient outward currents arise from microdomains where BK channels are exposed to a mean Ca(2+) concentration on the order of 10 microM during a Ca(2+) spark.
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Diminished surface clustering and increased perinuclear accumulation of large conductance Ca2+-activated K+ channel in mouse myometrium with pregnancyRegulation of cellular communication by signaling microdomains in the blood vessel wall.Sub-plasmalemmal [Ca2+]i upstroke in myocytes of the guinea-pig small intestine evoked by muscarinic stimulation: IP3R-mediated Ca2+ release induced by voltage-gated Ca2+ entryRACK1 is a BKCa channel binding protein.Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscleThe regulation of BK channel activity by pre- and post-translational modifications.Organization of Ca2+ release units in excitable smooth muscle of the guinea-pig urinary bladderCalcium mobilization and spontaneous transient outward current characteristics upon agonist activation of P2Y2 receptors in smooth muscle cells.Ethanol-mediated relaxation of guinea pig urinary bladder smooth muscle: involvement of BK and L-type Ca2+ channelsRole of mitochondria in contraction and pacemaking in the mouse uterus.Ion channels in smooth muscle: regulators of intracellular calcium and contractility.Syntillas release Ca2+ at a site different from the microdomain where exocytosis occurs in mouse chromaffin cells.Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signalingHeme is a carbon monoxide receptor for large-conductance Ca2+-activated K+ channelsEffects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs.Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca(2+) sparks in airway myocytesGenetic ablation of caveolin-1 modifies Ca2+ spark coupling in murine arterial smooth muscle cells.KCa channel insensitivity to Ca2+ sparks underlies fractional uncoupling in newborn cerebral artery smooth muscle cells.Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype.Caveolae-associated signalling in smooth muscle.Rhythmicity in arterial smooth muscle.Calcium events in smooth muscles and their interstitial cells; physiological roles of sparks.Mechanism of the inhibition of Ca2+-activated Cl- currents by phosphorylation in pulmonary arterial smooth muscle cellsSjogrens syndrome--the non-apoptotic model of glandular hypofunction.Hypoxia reduces KCa channel activity by inducing Ca2+ spark uncoupling in cerebral artery smooth muscle cellsConcerted vs. sequential. Two activation patterns of vast arrays of intracellular Ca2+ channels in muscle.A close association of RyRs with highly dense clusters of Ca2+-activated Cl- channels underlies the activation of STICs by Ca2+ sparks in mouse airway smooth muscle.Ca2+-sparks constitute elementary building blocks for global Ca2+-signals in myocytes of retinal arterioles.Transduction of voltage and Ca2+ signals by Slo1 BK channels.Suppression of Ca2+ syntillas increases spontaneous exocytosis in mouse adrenal chromaffin cellsImpaired function of coronary BK(Ca) channels in metabolic syndromeSarcoplasmic reticulum function in smooth muscle.Mitochondrial regulation of cytosolic Ca²⁺ signals in smooth muscle.Subplasma membrane Ca2+ signals.Regulation of gastrointestinal motility--insights from smooth muscle biology.The BK channel: a vital link between cellular calcium and electrical signaling.Examining the role of mitochondria in Ca²⁺ signaling in native vascular smooth muscleCa2+-activated K channels in parotid acinar cells: The functional basis for the hyperpolarized activation of BK channels.Ca(2+) spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K(+) channels, and coupling ratio between them.The beta1 subunit of the Ca2+-sensitive K+ channel protects against hypertension.
P2860
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P2860
Spontaneous transient outward currents arise from microdomains where BK channels are exposed to a mean Ca(2+) concentration on the order of 10 microM during a Ca(2+) spark.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Spontaneous transient outward ...... microM during a Ca(2+) spark.
@ast
Spontaneous transient outward ...... microM during a Ca(2+) spark.
@en
type
label
Spontaneous transient outward ...... microM during a Ca(2+) spark.
@ast
Spontaneous transient outward ...... microM during a Ca(2+) spark.
@en
prefLabel
Spontaneous transient outward ...... microM during a Ca(2+) spark.
@ast
Spontaneous transient outward ...... microM during a Ca(2+) spark.
@en
P2093
P2860
P356
P1476
Spontaneous transient outward ...... microM during a Ca(2+) spark.
@en
P2093
John V Walsh
Kevin E Fogarty
Richard A Tuft
Ronghua Zhuge
P2860
P356
10.1085/JGP.20028571
P577
2002-07-01T00:00:00Z