Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity - sprookjes - yvandenbroek - TriplyDB

Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity

Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity

http://www.wikidata.org/entity/Q36562670

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Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation Retinoic acid-related orphan receptor γ (RORγ): a novel participant in the diurnal regulation of hepatic gluconeogenesis and insulin sensitivity RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D.Circadian gene variants in cancer.Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genes.REV-ERB and ROR nuclear receptors as drug targets.The rs340874 PROX1 type 2 diabetes mellitus risk variant is associated with visceral fat accumulation and alterations in postprandial glucose and lipid metabolism Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism.Molecular Targets for Small-Molecule Modulators of Circadian Clocks.Mouse aldehyde-oxidase-4 controls diurnal rhythms, fat deposition and locomotor activity Genetic Variants of Retinoic Acid Receptor-Related Orphan Receptor Alpha Determine Susceptibility to Type 2 Diabetes Mellitus in Han Chinese.Isotretinoin increased carotid intima-media thickness in acne patients Xenobiotic Receptor-Mediated Regulation of Intestinal Barrier Function and Innate Immunity.RORα and RORγ expression inversely correlates with human melanoma progression.The biological clock and the molecular basis of lysosomal storage diseases.Metabolism of murine TH 17 cells: Impact on cell fate and function Th17 cells in Type 1 diabetes: a future perspective.On the role of classical and novel forms of vitamin D in melanoma progression and management.Retinoic acid receptor-related orphan receptor α stimulates adipose tissue inflammation by modulating endoplasmic reticulum stress.Retinoic acid-related orphan receptor C isoform 2 expression and its prognostic significance for non-small cell lung cancer.Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome.Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols.Obesity-induced inflammation and insulin resistance.Effects of MetAP2 inhibition on hyperphagia and body weight in Prader-Willi syndrome: A randomized, double-blind, placebo-controlled trial.The control of oligodendrocyte bioenergetics by interferon-gamma (IFN-γ) and Src homology region 2 domain-containing phosphatase-1 (SHP-1).Cadmium-Associated Differential Methylation throughout the Placental Genome: Epigenome-Wide Association Study of Two U.S. Birth Cohorts.Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems.Retinoic Acid Receptor-Related Orphan Receptors: Critical Roles in Tumorigenesis.

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Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity

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2013 nî lūn-bûn

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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Retinoic acid-related orphan r ...... ation, and insulin sensitivity

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Frontiers in Endocrinology

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Retinoic acid-related orphan r ...... ation, and insulin sensitivity

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Hong Soon Kang

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Yukimasa Takeda

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BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha

Insulin signalling and the regulation of glucose and lipid metabolism

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma

Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A

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Anton M. Jetten

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