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The Sweet Path to Metabolic Demise: Fructose and Lipid SynthesisKLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.The significance of beige and brown fat in humans.The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression.Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injuryRoux-en-Y gastric bypass surgery is effective in fibroblast growth factor-21 deficient mice.Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydratesA critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.Transcriptional coordination of hepatic autophagy by nutrient-sensing nuclear receptor PPARα and FXR.Fibroblast growth factor 21, assisted by elevated glucose, activates paraventricular nucleus NUCB2/Nesfatin-1 neurons to produce satiety under fed states.Fibroblast growth factor 21: a regulator of metabolic disease and health span.Targeting adipose tissue in the treatment of obesity-associated diabetes.Fgf21 regulates T-cell development in the neonatal and juvenile thymus.Macronutrient Intake-Associated FGF21 Genotype Modifies Effects of Weight-Loss Diets on 2-Year Changes of Central Adiposity and Body Composition: The POUNDS Lost Trial.The Role of Carbohydrate Response Element Binding Protein in Intestinal and Hepatic Fructose Metabolism.Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints.Lifestyle precision medicine: the next generation in type 2 diabetes prevention?A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response.Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns.Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis.Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury.FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.Once-weekly administration of a long-acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese people with hypertriglyceridaemia and in non-human primates.Intestinal, but not hepatic, ChREBP is required for fructose tolerance.Roux-en-Y Gastric Bypass Surgery Has Unique Effects on Postprandial FGF21 but Not FGF19 Secretion.FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.Prenatal androgen receptor activation determines adult alcohol and water drinking in a sex-specific way.FGF21 and metabolic disease in 2016: A new frontier in FGF21 biology.Fructose metabolism and metabolic disease.FGF 21 deficiency slows gastric emptying and reduces initial blood alcohol concentration in mice exposed to acute alcohol in fasting state.ChREBP refines the hepatic response to fructose to protect the liver from injury.Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice.A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure.FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest.Defining “FGF21 Resistance” during obesity: Controversy, criteria and unresolved questions.Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in miceFGF21 increases water intake, urine output and blood pressure in rats
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
FGF21 Regulates Sweet and Alcohol Preference.
@ast
FGF21 Regulates Sweet and Alcohol Preference.
@en
type
label
FGF21 Regulates Sweet and Alcohol Preference.
@ast
FGF21 Regulates Sweet and Alcohol Preference.
@en
prefLabel
FGF21 Regulates Sweet and Alcohol Preference.
@ast
FGF21 Regulates Sweet and Alcohol Preference.
@en
P2093
P2860
P50
P1433
P1476
FGF21 Regulates Sweet and Alcohol Preference
@en
P2093
Andrew Smith
Barbara Bernardo
Bryan Goodwin
Genaro Hernandez
Parkyong Song
Saswata Talukdar
Steven A Kliewer
Tod Turner
William T Scott
P2860
P304
P356
10.1016/J.CMET.2015.12.008
P577
2015-12-24T00:00:00Z