Tuning silence: conditional systems for RNA interference. - sprookjes - yvandenbroek - TriplyDB

Tuning silence: conditional systems for RNA interference.

Tuning silence: conditional systems for RNA interference.

http://www.wikidata.org/entity/Q36575390

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Controlled expression of functional miR-122 with a ligand inducible expression system Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?Light-dependent RNA interference with nucleobase-caged siRNAs Genetics in non-genetic model systems Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR A versatile viral system for expression and depletion of proteins in mammalian cells MicroRNA regulation of human protease genes essential for influenza virus replication Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: a comparative study.pHUSH: a single vector system for conditional gene expression Modeling recursive RNA interference.Heritable and lineage-specific gene knockdown in zebrafish embryo Automated microscopy for high-content RNAi screening Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines.Cell- and region-specific miR30-based gene knock-down with temporal control in the rat brain Identification of Schistosoma mansoni microRNAs Discovery of long-range inhibitory signaling to ensure single axon formation.Regulation of MAP4K4 gene expression by RNA interference through an engineered theophylline-dependent hepatitis delta virus ribozyme switch.Conditional Dicer substrate formation via shape and sequence transduction with small conditional RNAs.Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration.Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing.A modular lentiviral and retroviral construction system to rapidly generate vectors for gene expression and gene knockdown in vitro and in vivo Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells Inhibition of highly pathogenic PRRSV replication in MARC-145 cells by artificial microRNAs.Comparison of doxycycline delivery methods for Tet-inducible gene expression in a subcutaneous xenograft model.Tissue-specific and reversible RNA interference in transgenic mice.Cell Type-Specific and Inducible PTEN Gene Silencing by a Tetracycline Transcriptional Activator-Regulated Short Hairpin RNA.Functional effects of GRM1 suppression in human melanoma cells.Silencing of IkBβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo.Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: novel options by phosphorothioate-stimulated delivery.Rapid, controlled and intensive lentiviral vector-based RNAi.Progress and prospects: the design and production of plasmid vectors.Lentiviral delivery of short hairpin RNAs Drug target discovery using retroviruses.Use of RNA interference by in utero electroporation to study cortical development: the example of the doublecortin superfamily.Inducible RNAi system and its application in novel therapeutics.Potent microRNA suppression by RNA Pol II-transcribed 'Tough Decoy' inhibitors.A bidirectional promoter architecture enhances lentiviral transgenesis in embryonic and extraembryonic stem cells.Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice.Inducible Bcl-2 gene RNA interference mediated by aptamer-integrated HDV ribozyme switch.Tissue-engineered cartilage with inducible and tunable immunomodulatory properties.

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P2860

Tuning silence: conditional systems for RNA interference.

http://www.wikidata.org/entity/Q36575390

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Tuning silence: conditional systems for RNA interference.

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Tuning silence: conditional systems for RNA interference.

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Didier Trono

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Jolanta Szulc

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Maciej Wiznerowicz

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P2860

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter.

CRE recombinase-inducible RNA interference mediated by lentiviral vectors

PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.

Cre-lox-regulated conditional RNA interference from transgenes

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences

Mammalian genome targeting using site-specific recombinases

PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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682-688

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10.1038/NMETH914

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9

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