Optimization of targeted RNA recombination and mapping of a novel nucleocapsid gene mutation in the coronavirus mouse hepatitis virus
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Engineering the largest RNA virus genome as an infectious bacterial artificial chromosomeCoronavirus particle assembly: primary structure requirements of the membrane protein.Characterization of an essential RNA secondary structure in the 3' untranslated region of the murine coronavirus genomeA bulged stem-loop structure in the 3' untranslated region of the genome of the coronavirus mouse hepatitis virus is essential for replicationConstruction of murine coronavirus mutants containing interspecies chimeric nucleocapsid proteins.Improved microarray gene expression profiling of virus-infected cells after removal of viral RNAPathogenesis of chimeric MHV4/MHV-A59 recombinant viruses: the murine coronavirus spike protein is a major determinant of neurovirulence.Analysis of constructed E gene mutants of mouse hepatitis virus confirms a pivotal role for E protein in coronavirus assemblyImportance of the positive-strand RNA secondary structure of a murine coronavirus defective interfering RNA internal replication signal in positive-strand RNA synthesis.Targeted recombination within the spike gene of murine coronavirus mouse hepatitis virus-A59: Q159 is a determinant of hepatotropism.Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrierInsertion of a new transcriptional unit into the genome of mouse hepatitis virus.Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivoDownstream sequences influence the choice between a naturally occurring noncanonical and closely positioned upstream canonical heptameric fusion motif during bovine coronavirus subgenomic mRNA synthesis.Subgenomic messenger RNA amplification in coronavirusesA mechanism of virus-induced demyelination.Dependence of coronavirus RNA replication on an NH2-terminal partial nonstructural protein 1 in cis.A major determinant for membrane protein interaction localizes to the carboxy-terminal domain of the mouse coronavirus nucleocapsid protein.Identification of cis-acting elements on positive-strand subgenomic mRNA required for the synthesis of negative-strand counterpart in bovine coronavirus.The coronavirus nucleocapsid is a multifunctional protein.An interaction between the nucleocapsid protein and a component of the replicase-transcriptase complex is crucial for the infectivity of coronavirus genomic RNA.Effect of mutations in the mouse hepatitis virus 3'(+)42 protein binding element on RNA replication.Genetic evidence for a structural interaction between the carboxy termini of the membrane and nucleocapsid proteins of mouse hepatitis virus.Coronaviruses maintain viability despite dramatic rearrangements of the strictly conserved genome organizationBovine coronavirus 5'-proximal genomic acceptor hotspot for discontinuous transcription is 65 nucleotides wide.Evaluation of the role of heterogeneous nuclear ribonucleoprotein A1 as a host factor in murine coronavirus discontinuous transcription and genome replication.Switching species tropism: an effective way to manipulate the feline coronavirus genome.The small envelope protein E is not essential for murine coronavirus replication.Murine coronavirus-induced hepatitis: JHM genetic background eliminates A59 spike-determined hepatotropismThe 3' cis-acting genomic replication element of the severe acute respiratory syndrome coronavirus can function in the murine coronavirus genome.Analysis of second-site revertants of a murine coronavirus nucleocapsid protein deletion mutant and construction of nucleocapsid protein mutants by targeted RNA recombination.Characterization of a murine coronavirus defective interfering RNA internal cis-acting replication signal.cis Requirement for N-specific protein sequence in bovine coronavirus defective interfering RNA replication.Replication of murine coronavirus defective interfering RNA from negative-strand transcripts.The internal open reading frame within the nucleocapsid gene of mouse hepatitis virus encodes a structural protein that is not essential for viral replicationAnalysis of a recombinant mouse hepatitis virus expressing a foreign gene reveals a novel aspect of coronavirus transcriptionAn RNA stem-loop within the bovine coronavirus nsp1 coding region is a cis-acting element in defective interfering RNA replication.A contemporary view of coronavirus transcription.Requirement of the 5'-end genomic sequence as an upstream cis-acting element for coronavirus subgenomic mRNA transcription.Identification of the cis-acting signal for minus-strand RNA synthesis of a murine coronavirus: implications for the role of minus-strand RNA in RNA replication and transcription
P2860
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P2860
Optimization of targeted RNA recombination and mapping of a novel nucleocapsid gene mutation in the coronavirus mouse hepatitis virus
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
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1994年论文
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name
Optimization of targeted RNA r ...... onavirus mouse hepatitis virus
@ast
Optimization of targeted RNA r ...... onavirus mouse hepatitis virus
@en
type
label
Optimization of targeted RNA r ...... onavirus mouse hepatitis virus
@ast
Optimization of targeted RNA r ...... onavirus mouse hepatitis virus
@en
prefLabel
Optimization of targeted RNA r ...... onavirus mouse hepatitis virus
@ast
Optimization of targeted RNA r ...... onavirus mouse hepatitis virus
@en
P2093
P2860
P1433
P1476
Optimization of targeted RNA r ...... onavirus mouse hepatitis virus
@en
P2093
P2860
P304
P407
P577
1994-01-01T00:00:00Z