NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
about
SNARE-dependent upregulation of potassium chloride co-transporter 2 activity after metabotropic zinc receptor activation in rat cortical neurons in vitroLong-range and short-range tumor-stroma networks synergistically contribute to tumor-associated epilepsy.Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockoutsCurrent view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2Neuronal and astroglial correlates underlying spatiotemporal intrinsic optical signal in the rat hippocampal sliceGABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy.Regulation of neuronal pH by the metabotropic Zn(2+)-sensing Gq-coupled receptor, mZnR/GPR39.Elevated intracellular chloride level in albino visual cortex neurons is mediated by Na-K-Cl co-transporter.Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2Cell-type specific distribution of chloride transporters in the rat suprachiasmatic nucleus.Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain.Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus.Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.Contribution of the potassium-chloride co-transporter KCC2 to the modulation of lumbar spinal networks in mice.Characterization of an epilepsy-associated variant of the human Cl-/HCO3(-) exchanger AE3.Altered GABA signaling in early life epilepsies.Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophreniaKinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.Highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter KCC2Bumetanide inhibits rapid kindling in neonatal rats.Novel functions of GABA signaling in adult neurogenesis.Physiology and pathophysiology of SLC12A1/2 transporters.GABAergic depolarization during early cortical development and implications for anticonvulsive therapy in neonates.Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus.Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy.Genetic predisposition and early life experience interact to determine glutamate transporter (GLT1) and solute carrier family 12 member 5 (KCC2) levels in rat hippocampus.WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.On the contribution of KCC2 and carbonic anhydrase to two types of in vitro interictal discharge.Reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memory.Chronic stress shifts the GABA reversal potential in the hippocampus and increases seizure susceptibility.Contribution of GABAergic interneurons to the development of spontaneous activity patterns in cultured neocortical networks.Perirhinal cortex hyperexcitability in pilocarpine-treated epileptic rats.Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe.Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival.Sini powder () decoction alleviates mood disorder of insomnia by regulating cation-chloride cotransporters in hippocampus.Improving emotional face perception in autism with diuretic bumetanide: a proof-of-concept behavioral and functional brain imaging pilot study.Pro-Brain-Derived Neurotrophic Factor (proBDNF)-Mediated p75NTR Activation Promotes Depolarizing Actions of GABA and Increases Susceptibility to Epileptic Seizures.
P2860
Q24617826-6A0A6EF2-59B2-4A13-9D7A-7FB658FD1AABQ26766290-AAD5979F-AA70-4F2D-830B-010EB7A7D1ECQ26829362-183A6C22-16EE-45A6-AC63-30AFB6946695Q26864902-A31C3D2C-0509-426D-8C45-3E3C5CAC8DC9Q27004031-47E20401-7065-4EAF-9333-A4070159B697Q27312501-0677C56A-D37E-4CDB-A0E7-46C38B50950BQ27335346-0357CE11-E502-47E5-A878-BF2F6CEC4E23Q30665208-DA8983D2-AAC9-4C6F-B4E4-7F67D8CE7CE4Q33347896-B247A421-774E-41D8-A0E6-7CEE993798A6Q33417208-88BFA434-377C-4E83-AFF4-56700CCD661AQ33624862-BF9673CD-F9D3-44F7-8B72-B620D10C157FQ33628412-321CE6DB-A764-41F9-8199-97A906862835Q34016647-96F51454-3CD6-4990-A359-25722C202D2BQ34026277-C570B1E5-A6A9-4313-ACAF-46A657DDE593Q34160178-E9806FD4-DB4A-42D8-9DE9-6EEE69E1112DQ34992473-D6710CDB-1355-4CE8-A00F-28B15E36527CQ35147300-90529261-EC9C-446C-94FA-D6236A460F4AQ35812578-8A7D629B-B570-451B-ADA0-F0878A9CBCD5Q35900778-3F567BF1-BBEE-45D3-9BC2-9F404D5F4AA4Q36145999-59D814A4-63BD-4BEC-9285-F3F27EC92120Q36598125-46004A2F-6E7F-47E0-8015-C24BC02F8B99Q37294436-CD34A9EF-86F5-4241-9840-2C10B0C697D5Q37320851-DD147829-7B1E-4648-A299-47F33E353DC1Q37341254-A66C8FB3-2A8A-48E4-87D8-5B209A4A38D3Q37424563-9BA3776C-DED5-42B2-AF00-57514247F546Q37888732-C0D110A1-BF84-499C-8E92-76258F82059CQ38912212-26DDC620-754C-4382-877C-2564C881B527Q38984830-32CE7E14-543D-4DAE-84B0-4B18131AD162Q40435442-33E78B38-7040-440B-AD15-507F44D9D39AQ40781213-90D74A1F-D2BC-4BF0-A8B7-7A93A3FBE0ADQ41555636-55CFC338-1E0C-41B0-99A3-E7FF6D7D832EQ41643247-C2E44AFD-83AC-4D62-8090-069135C0751CQ41668962-3DFE4DDD-D273-4288-B66D-5D5780C97C9CQ42090506-EF9603FA-8589-40E4-85D0-186BADE4B404Q42145615-E310FD51-4330-4CA3-9C2C-C6D5E98DFE7BQ42224632-72C3DCAC-8856-453F-8AC0-6200120B547AQ45331093-DBC4FFDF-9F71-455D-9F50-DCA5CABB9A62Q47915856-13159111-E6E5-4DDB-83BF-7F862509BCCBQ47942709-457F3EFF-7785-436C-94F8-1AC97D2579CDQ48408039-CB1C81F5-1579-423D-947E-9D7C558165C0
P2860
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
@ast
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
@en
type
label
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
@ast
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
@en
prefLabel
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
@ast
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
@en
P2093
P2860
P1433
P1476
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
@en
P2093
Eric Delpire
Gregory C Mathews
Nathan Polley
P2860
P304
P356
10.1016/J.EPLEPSYRES.2008.02.005
P577
2008-04-03T00:00:00Z