Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.
about
Steroid hormone receptors and prostate cancer: role of structural dynamics in therapeutic targetingA sting in the tail: the N-terminal domain of the androgen receptor as a drug targetWhat's new in estrogen receptor action in the female reproductive tractSynthetic androgens as designer supplementsThe prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancerAndrogen induces a switch from cytoplasmic retention to nuclear import of the androgen receptorThe link between androgen receptor splice variants and castration-resistant prostate cancer.Lipid metabolism emerges as a promising target for malignant glioma therapy.The role of genetics in estrogen responses: a critical piece of an intricate puzzle.Comparing the rules of engagement of androgen and glucocorticoid receptorsThe synthetic glucocorticoids prednisolone and dexamethasone regulate the same genes in acute lymphoblastic leukemia cells.Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry.Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizationsSolution Behavior of the Intrinsically Disordered N-Terminal Domain of Retinoid X Receptor α in the Context of the Full-Length Protein.Variable steroid receptor responses: Intrinsically disordered AF1 is the key.Phosphorylation: a fundamental regulator of steroid receptor action.Regulation of the structurally dynamic N-terminal domain of progesterone receptor by protein-induced folding.Dissection of androgen receptor-promoter interactions: steroid receptors partition their interaction energetics in parallel with their phylogenetic divergence.Trinucleotide repeats and protein folding and disease: the perspective from studies with the androgen receptor.Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges.Steroid receptor-DNA interactions: toward a quantitative connection between energetics and transcriptional regulationAnalysis of a glucocorticoid-estrogen receptor chimera reveals that dimerization energetics are under ionic controlIQGAP1 binds to estrogen receptor-α and modulates its function.Revisiting ligand-induced conformational changes in proteins: essence, advancements, implications and future challenges.Role of androgen receptor polyQ chain elongation in Kennedy's disease and use of natural osmolytes as potential therapeutic targets.Androgen receptor modulators: a marriage of chemistry and biology.Steroid hormones, receptors, and perceptual and cognitive sex differences in the visual system.Binding of bisphenol A, bisphenol AF, and bisphenol S on the androgen receptor: Coregulator recruitment and stimulation of potential interaction sites.Trehalose induces functionally active conformation in the intrinsically disordered N-terminal domain of glucocorticoid receptor.Estrogen Deficiency and the Origin of Obesity during MenopauseTargeting constitutively active androgen receptor splice variants in castration resistant prostate cancerDNA-induced unfolding of the thyroid hormone receptor α A/B domain through allostery.Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor.Steroids and the brain: 50years of research, conceptual shifts and the ascent of non-classical and membrane-initiated actions.SH binds SHR within the HSP90 chaperone complexThe Nuclear Receptor Superfamily at Thirty.The Nuclear Receptor Field: A Historical Overview and Future Challenges
P2860
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P2860
Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Allosteric modulators of stero ...... dynamics and gene regulation.
@ast
Allosteric modulators of stero ...... dynamics and gene regulation.
@en
type
label
Allosteric modulators of stero ...... dynamics and gene regulation.
@ast
Allosteric modulators of stero ...... dynamics and gene regulation.
@en
prefLabel
Allosteric modulators of stero ...... dynamics and gene regulation.
@ast
Allosteric modulators of stero ...... dynamics and gene regulation.
@en
P2860
P356
P1433
P1476
Allosteric modulators of stero ...... dynamics and gene regulation.
@en
P2093
Iain J McEwan
P2860
P304
P356
10.1210/ER.2011-1033
P577
2012-03-20T00:00:00Z