A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter.
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Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization.CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomasBCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent mannerDevelopmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytesGenetic polymorphisms of Bcl-2 promoter in cancer susceptibility and prognosis: a meta-analysis.Effect of Modulation of hnRNP L Levels on the Decay of bcl-2 mRNA in MCF-7 Cells.LIN-35/Rb causes starvation-induced germ cell apoptosis via CED-9/Bcl2 downregulation in Caenorhabditis elegans.Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide.BCL-2 (-938C > A) polymorphism is associated with breast cancer susceptibility.Structural insights into G-quadruplexes: towards new anticancer drugs.17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence.Upregulation of cellular Bcl-2 by the KSHV encoded RTA promotes virion productionThe major G-quadruplex formed in the human BCL-2 proximal promoter adopts a parallel structure with a 13-nt loop in K+ solutionPar-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.BCL2 genotypes: functional and neurobehavioral outcomes after severe traumatic brain injury.A genetic variant of p53 restricts the mucous secretory phenotype by regulating SPDEF and Bcl-2 expression.The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia.NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter regionFunctional BCL-2 regulatory genetic variants contribute to susceptibility of esophageal squamous cell carcinoma.A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements.The AML1/ETO fusion protein activates transcription of BCL-2BCL2-938C>A and CALCA-1786T>C polymorphisms in aseptic loosened total hip arthroplastyPolymorphisms of BCL2 and BAX Genes Associate with Outcomes in Advanced Non-small cell lung cancer Patients treated with platinum-based Chemotherapy.Cell death regulation by B-cell lymphoma protein.Study of regulatory promoter polymorphism (-248 G>A) of Bax gene in patients with gastric cancer in the northern provinces of Iran.Identification of a novel Bcl-2 promoter region that counteracts in a p53-dependent manner the inhibitory P2 region.Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosisA novel SATB1 binding site in the BCL2 promoter region possesses transcriptional regulatory functionSilencer elements controlling the B29 (Igbeta) promoter are neither promoter- nor cell-type-specificAn intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solutionDeconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter.Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions.A New G-Quadruplex with Hairpin Loop Immediately Upstream of the Human BCL2 P1 Promoter Modulates Transcription.Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs.DNA damage-binding complex recruits HDAC1 to repress Bcl-2 transcription in human ovarian cancer cells.Study of the regulatory promoter polymorphism (-938C>A) of B-cell lymphoma 2 gene in breast cancer patients of Mazandaran province in Northern Iran.Genetic determinants of neuronal vulnerability to apoptosis.A transcriptional regulatory element in the coding sequence of the human Bcl-2 gene.Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor.
P2860
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P2860
A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
A negative regulatory element ...... ion from an upstream promoter.
@ast
A negative regulatory element ...... ion from an upstream promoter.
@en
type
label
A negative regulatory element ...... ion from an upstream promoter.
@ast
A negative regulatory element ...... ion from an upstream promoter.
@en
prefLabel
A negative regulatory element ...... ion from an upstream promoter.
@ast
A negative regulatory element ...... ion from an upstream promoter.
@en
P2860
P356
P1476
A negative regulatory element ...... ion from an upstream promoter.
@en
P2093
S J Korsmeyer
P2860
P304
P356
10.1128/MCB.13.6.3686
P407
P577
1993-06-01T00:00:00Z