O-methylated metabolite of 7,8-dihydroxyflavone activates TrkB receptor and displays antidepressant activity.
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7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disordersNeuroprotective Effects of 7, 8-dihydroxyflavone on Midbrain Dopaminergic Neurons in MPP(+)-treated Monkeys7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease.7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis.New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases.Activation of muscular TrkB by its small molecular agonist 7,8-dihydroxyflavone sex-dependently regulates energy metabolism in diet-induced obese mice.Probing the ability of presynaptic tyrosine kinase receptors to regulate striatal dopamine dynamics.Chronic TrkB agonist treatment in old age does not mitigate diaphragm neuromuscular dysfunction.Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome.The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer's disease.Biosynthesis of novel 7,8-dihydroxyflavone glycoside derivatives and in silico study of their effects on BACE1 inhibition.Antidepressant Flavonoids and Their Relationship with Oxidative Stress.Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer's disease.
P2860
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P2860
O-methylated metabolite of 7,8-dihydroxyflavone activates TrkB receptor and displays antidepressant activity.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
O-methylated metabolite of 7,8 ...... plays antidepressant activity.
@ast
O-methylated metabolite of 7,8 ...... plays antidepressant activity.
@en
type
label
O-methylated metabolite of 7,8 ...... plays antidepressant activity.
@ast
O-methylated metabolite of 7,8 ...... plays antidepressant activity.
@en
prefLabel
O-methylated metabolite of 7,8 ...... plays antidepressant activity.
@ast
O-methylated metabolite of 7,8 ...... plays antidepressant activity.
@en
P2093
P2860
P356
P1433
P1476
O-methylated metabolite of 7,8 ...... plays antidepressant activity.
@en
P2093
P2860
P304
P356
10.1159/000346920
P577
2013-02-21T00:00:00Z