AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model.
about
An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imagingAn MDS xenograft model utilizing a patient-derived cell line.Cellular intrinsic mechanism affecting the outcome of AML treated with Ara-C in a syngeneic mouse model.Site-Specific Drug-Releasing Polypeptide Nanocarriers Based on Dual-pH Response for Enhanced Therapeutic Efficacy against Drug-Resistant Tumors.Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid LeukemiaA ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway CompoundsEfficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice.Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formationTherapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: a new tool to decipher their chemoresistance and self-renewal mechanisms.Functional heterogeneity of genetically defined subclones in acute myeloid leukemiaOverexpression of Hiwi Inhibits the Cell Growth of Chronic Myeloid Leukemia K562 Cells and Enhances Their Chemosensitivity to Daunomycin.The role of the proteasome in AML.Patient-derived xenograft (PDX) models in basic and translational breast cancer research.Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias.Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells.c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish.Phosphodiesterase 5 inhibitor acts as a potent agent sensitizing acute myeloid leukemia cells to 67-kDa laminin receptor-dependent apoptosis.Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.Gemtuzumab Ozogamicin (GO) Inclusion to Induction Chemotherapy Eliminates Leukemic Initiating Cells and Significantly Improves Survival in Mouse Models of Acute Myeloid Leukemia.R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling.Are we ready to take full advantage of patient-derived tumor xenograft models?Preventing chemotherapy-induced myelosuppression by repurposing the FLT3 inhibitor quizartinib.Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.IGH/MYC Translocation Associates with BRCA2 Deficiency and Synthetic Lethality to PARP1 Inhibitors.FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.RNA N6-methyladenosine modification in cancers: current status and perspectives.LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia.Intramuscular Transplantation Improves Engraftment Rates for Esophageal Patient-Derived Tumor Xenografts.Targeting chemotherapy-resistant leukemia by combining DNT cellular therapy with conventional chemotherapy.IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML
P2860
Q27311229-97665A92-D365-408A-AFC7-DA4DBFE25FE9Q34433095-E8044AD7-CB6D-40E4-952C-00B15520EB2AQ35331086-6CCF013F-D372-45DB-8A0E-36F66C312EDAQ35633363-9C4F78F2-BE60-4C9A-AEB4-7501862D88C3Q35692708-26D9C365-1AFE-421A-835F-A834613B95C6Q35792527-26A9E76C-8A80-4C95-B194-8A07C684213DQ35800831-750F1D5A-AEA4-4DFA-A302-871AAAB1C1F0Q36008395-9B5B650A-0636-4725-8018-FEBC65E2A7C0Q36070463-352D23C2-721E-49A7-9AC1-F86AB4DFD145Q37410557-4BBAD430-36B5-4F06-8EB3-2578E22EF417Q37681007-B888D6C7-3925-4880-8530-8BAC022949BFQ37698123-5D587A86-836C-4C7F-9EDC-42668045585EQ38907442-5D0DFC0F-40E7-4D0E-AF8E-9791D7CB0B19Q39027087-E6387BD8-D550-4139-A13A-70E4C8EE92A1Q39057246-F9D5FB78-D529-4CB5-9222-0A0CD68BD8BCQ39642260-924297E6-98BB-4D46-A0ED-3E03B14433FAQ41964099-9A3D13BB-89F5-4C4B-9C86-D4D22AB5A915Q42375720-1D41C443-94A9-4EC7-B1D7-D7921C839D5BQ43487946-F46FF662-61FA-4BFA-A70B-992FF20E56D4Q44980700-8F09BFCD-CF05-47B7-B200-D79DF69F1D9AQ46381905-27358638-683E-4DED-82B0-C4D44282F3C7Q47139006-4A217E3F-5425-4AEB-B0D8-ACC240DB07ECQ47284426-FD9E97DD-E8C3-45CD-8743-CBD44F750720Q48099042-B7E7F580-BB18-437F-B635-2EB0D66304FFQ48263650-D7BA5CC9-5035-4CE9-B79E-2D506A5AFC23Q49165603-73D5EF83-9469-4DC8-AC8C-607339519433Q50933002-954A98C1-B6A5-4662-8813-38BA29DAEC90Q51236778-6CB0CA08-CB8E-4F00-A55F-766C0FA1F783Q52311777-6C6EA032-75AD-4797-9AE3-9D4014F8F934Q52430746-7B950718-C248-4931-BCAB-1A8F8D9A6B13Q52966216-C7FBCA25-1621-4E18-9736-A068D2F1308DQ55090588-51E54804-DABD-4BA3-B75B-94B1EA1481ECQ57927278-227AF801-9FB8-4C64-B051-C11090722090
P2860
AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
AML cells are differentially s ...... nt in a human xenograft model.
@ast
AML cells are differentially s ...... nt in a human xenograft model.
@en
type
label
AML cells are differentially s ...... nt in a human xenograft model.
@ast
AML cells are differentially s ...... nt in a human xenograft model.
@en
prefLabel
AML cells are differentially s ...... nt in a human xenograft model.
@ast
AML cells are differentially s ...... nt in a human xenograft model.
@en
P2093
P2860
P1433
P1476
AML cells are differentially s ...... ent in a human xenograft model
@en
P2093
Benjamin Mizukawa
Christina Sexton
James C Mulloy
Mahesh Shrestha
Mark Wunderlich
Yogen Saunthararajah
P2860
P356
10.1182/BLOOD-2012-10-464677
P407
P577
2013-01-24T00:00:00Z