The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage
about
The OXR domain defines a conserved family of eukaryotic oxidation resistance proteinsSuppression of UV-induced apoptosis by the human DNA repair protein XPGFunctional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulationStructures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteomeThe transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription.SUB1 Plays a Negative Role during Starvation Induced Sporulation Program in Saccharomyces cerevisiae.Genome-wide location analysis reveals a role for Sub1 in RNA polymerase III transcription.Differential requirement for SUB1 in chromosomal and plasmid double-strand DNA break repairPositive Cofactor 4 (PC4) is critical for DNA repair pathway re-routing in DT40 cellsDisruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast GenesRecruitment of RNA polymerase II cofactor PC4 to DNA damage sitesSpaceflight alters the gene expression profile of cervical cancer cells.Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNAStructural/functional analysis of the human OXR1 protein: identification of exon 8 as the anti-oxidant encoding function.Effect of labeling with iron oxide particles or nanodiamonds on the functionality of adipose-derived mesenchymal stem cellsTranscriptional coactivator PC4, a chromatin-associated protein, induces chromatin condensation.Induction of a unique isoform of the NCOA7 oxidation resistance gene by interferon β-1b.PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites.Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells.Inhibition of human positive cofactor 4 radiosensitizes human esophageal squmaous cell carcinoma cells by suppressing XLF-mediated nonhomologous end joiningSilibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblastsThe 3' processing factor CstF functions in the DNA repair responseXPG Gene Polymorphisms Contribute to Colorectal Cancer Susceptibility: A Two-Stage Case-Control Study.A global transcription cofactor bound to juxtaposed strands of unwound DNA.A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4.Novel XPG (ERCC5) mutations affect DNA repair and cell survival after ultraviolet but not oxidative stress.p53 regulates its own activator: transcriptional co-activator PC4, a new p53-responsive gene.Human positive coactivator 4 is a potential novel therapeutic target in non-small cell lung cancer.Sub1/PC4, a multifaceted factor: from transcription to genome stability.SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence.Activation of p53 function by human transcriptional coactivator PC4: role of protein-protein interaction, DNA bending, and posttranslational modifications.The Sub1 nuclear protein protects DNA from oxidative damageIdentification of the ssDNA-binding protein of bacteriophage T5: Implications for T5 replication.Pellagra-like condition is xeroderma pigmentosum/Cockayne syndrome complex and niacin confers clinical benefit.Identification of redox-sensitive cysteines in the Arabidopsis proteome using OxiTRAQ, a quantitative redox proteomics method.AtCOX10, a protein involved in haem o synthesis during cytochrome c oxidase biogenesis, is essential for plant embryogenesis and modulates the progression of senescence.Def1 and Dst1 play distinct roles in repair of AP lesions in highly transcribed genomic regions.Inhibition of PC4 radiosensitizes non-small cell lung cancer by transcriptionally suppressing XLF.
P2860
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P2860
The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The single-strand DNA binding ...... illing by oxidative DNA damage
@ast
The single-strand DNA binding ...... illing by oxidative DNA damage
@en
type
label
The single-strand DNA binding ...... illing by oxidative DNA damage
@ast
The single-strand DNA binding ...... illing by oxidative DNA damage
@en
prefLabel
The single-strand DNA binding ...... illing by oxidative DNA damage
@ast
The single-strand DNA binding ...... illing by oxidative DNA damage
@en
P2093
P2860
P1476
The single-strand DNA binding ...... illing by oxidative DNA damage
@en
P2093
Altaf Hossain Sarker
Jen-Yeu Wang
Michael R Volkert
Priscilla K Cooper
P2860
P304
P356
10.1128/MCB.24.13.6084-6093.2004
P407
P577
2004-07-01T00:00:00Z