Transgenic mouse model for central nervous system demyelination.
about
Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas.Molecular pathways of oligodendrocyte apoptosis revealed by mutations in the proteolipid protein gene.Repression of the NF1 gene by Tax may expain the development of neurofibromas in human T-lymphotropic virus type 1 transgenic mice.Disrupted proteolipid protein trafficking results in oligodendrocyte apoptosis in an animal model of Pelizaeus-Merzbacher disease.The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic ratsMyelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expressionReproductive and neurological Quaking(viable) phenotypes in a severe combined immune deficient mouse backgroundts1-Induced spongiform encephalomyelopathy: physical forms of high-mobility DNA in spinal cord tissues of paralyzed mice are products of premature termination of reverse transcription.Dysmyelination in class I MHC transgenic mice.A cellular mechanism governing the severity of Pelizaeus-Merzbacher disease.Morphological and molecular response of the MOCH-1 oligodendrocyte cell line to serum and interferon-gamma: possible implications for demyelinating disorders.Many naturally occurring mutations of myelin proteolipid protein impair its intracellular transport.The effects of interferon-gamma on the central nervous system.Transcriptional regulation of MHC class I gene expression in rat oligodendrocytes.Vacuolar myelopathy in transgenic mice expressing human immunodeficiency virus type 1 proteins under the regulation of the myelin basic protein gene promoter.Human class I major histocompatibility complex transgene prevents virus-induced demyelination in susceptible mutant B10.D2dml mice.Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes.The proximal region of the MBP gene promoter is sufficient to induce oligodendroglial-specific expression in transgenic mice.A minimal human MBP promoter-lacZ transgene is appropriately regulated in developing brain and after optic enucleation, but not in shiverer mutant mice.Targeted expression of Cre recombinase to myelinating cells of the central nervous system in transgenic mice.
P2860
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P2860
Transgenic mouse model for central nervous system demyelination.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Transgenic mouse model for central nervous system demyelination.
@en
type
label
Transgenic mouse model for central nervous system demyelination.
@en
prefLabel
Transgenic mouse model for central nervous system demyelination.
@en
P2093
P2860
P356
P1476
Transgenic mouse model for central nervous system demyelination.
@en
P2093
P2860
P304
P356
10.1128/MCB.11.11.5479
P407
P577
1991-11-01T00:00:00Z