%D8%B3%D9%8A%D9%83%D9%84%D9%88%D8%B3%D8%A8%D9%88%D8%B1%D9%8A%D9%86%D8%B3%DB%8C%DA%A9%D9%84%D9%88%D8%B3%D9%BE%D9%88%D8%B1%DB%8C%D9%86CiclosporinaCategory:CiclosporinCiclosporinCiclosporinCiclosporinCiclosporina%D8%B3%DB%8C%DA%A9%D9%84%D9%88%D8%B3%D9%BE%D9%88%D8%B1%DB%8C%D9%86SiklosporiiniCiclosporine%D7%A6%D7%99%D7%A7%D7%9C%D7%95%D7%A1%D7%A4%D7%95%D7%A8%D7%99%D7%9FCiklosporinSiklosporinaCiclosporina%E3%82%B7%E3%82%AF%E3%83%AD%E3%82%B9%E3%83%9D%E3%83%AA%E3%83%B3%EC%8B%9C%ED%81%B4%EB%A1%9C%EC%8A%A4%ED%8F%AC%EB%A6%B0%D0%A6%D0%B8%D0%BA%D0%BB%D0%BE%D1%81%D0%BF%D0%BE%D1%80%D0%B8%D0%BDSiklosporinaCiclosporineCiklosporin%E0%AC%B8%E0%AC%BF%E0%AC%95%E0%AD%8D%E0%AC%B2%E0%AD%8B%E0%AC%B8%E0%AD%8D%E0%AC%AA%E0%AD%8B%E0%AC%B0%E0%AC%BF%E0%AC%A8CyklosporynaCiclosporina%D0%A6%D0%B8%D0%BA%D0%BB%D0%BE%D1%81%D0%BF%D0%BE%D1%80%D0%B8%D0%BDCiklosporinCiklosporinCiklosporinCiklosporin%D0%A6%D0%B8%D0%BA%D0%BB%D0%BE%D1%81%D0%BF%D0%BE%D1%80%D0%B8%D0%BDCiclosporinQ367700%E7%8E%AF%E5%AD%A2%E7%B4%A0
about
interstitial lung diseaseadult-onset Still's diseasegraft-versus-host diseasefocal segmental glomerulosclerosissystemic lupus erythematosusmembranous glomerulonephritisrheumatoid arthritisErythroblastopeniaacropustulosisnephrotic syndromebronchiolitis obliteransautoimmune diseasemyasthenia gravisBehcet's diseasemyelodysplastic syndrome
P2176
Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous DiseaseFludarabine Phosphate, Low-Dose Total-Body Irradiation, and Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Older Patients With Chronic Myeloid LeukemiaPK, Safety & Tolerability of CyCol® Versus Sandimmune® in Healthy SubjectsComparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell TransplantationDose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental GlomerulosclerosisPK Study of Tacrolimus and Cyclosporine When Co-Administered With Adefovir Dipivoxil in Post-Liver Transplant PatientsTacrolimus as Secondary Intervention vs. Continuation of Cyclosporine in Renal Transplant Patients With Chronic Renal Allograft Failure (CRAF)Nonmyeloablative Allo SCT for the Treatment of Hematologic DisordersEvaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant RecipientsCyclosporine Inhalation Solution (CIS) in Lung Transplant RecipientsFibrosis in Renal AllograftsAntithymocyte Globulin and Cyclosporine in Treating Low Risk Patients With Myelodysplastic SyndromeReduction in the Risk of Rejection by Mycophenolate Mofetil Dose Adjustment in Liver Transplant Patients With Side Effects Caused by the Calcineurine InhibitorsFludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi AnemiaStudy Evaluating of Calcineurin Inhibitors Versus Sirolimus in Renal Allograft RecipientStudy Evaluating Sirolimus and Cyclosporine in Kidney Transplant RecipientsA Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative RegimenTreatment Protocol for Hemophagocytic Lymphohistiocytosis 2004Cyclosporin A Eye Drop Treatment in Vernal KeratoconjunctivitisChemotherapy, Total-Body Irradiation, Rituximab, and Donor Stem Cell Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic LeukemiaHSP-glomerulonephritis Trial: MP vs CyAEfficacy and Safety of Everolimus in Combination With Cyclosporine Microemulsion Versus Everolimus in Combination With Enteric-coated Mycophenolate Sodium (EC-MPS), in Adult Renal Transplant Patients in Maintenance.Shift to Everolimus (RAD) Kidney Sparing StudyEvaluation of the Therapeutic Benefit of an Initial Intensified Dosing Regimen of Mycophenolate Sodium Versus a Standard Regimen in Renal Transplant PatientsNitrate and Hypertension in Heart Transplanted PatientsStudy to Assess LX201 for Prevention of Corneal Allograft Rejection or Graft Failure in Subjects Who Have Experienced One or More Rejection Episodes Following Penetrating KeratoplastyStudy to Assess the Efficacy and Safety of LX201 for Prevention of Corneal Allograft Rejection Episodes and Graft Failure in Subjects at Increased Immunological RiskPrednisolone vs. Ciclosporine in Severe Atopic EczemaPharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant PatientsEverolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host DiseaseSOCRATES: Steroid or Cyclosporine Removal After Transplantation Using EverolimusStudy Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant RecipientsIntensified vs. Standard Dose Therapy With Mycophenolate Sodium Plus Cyclosporin Microemulsion and Corticosteroid Combination in Patients With de Novo Renal Transplant PatientsCombination Chemotherapy and Total-Body Irradiation Before Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer, Metastatic Breast Cancer, or Kidney CancerEffect of Cyclosporine Therapy on Gene Expression in Patients With Large Granular Lymphocyte LeukemiaDonor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic MalignanciesPilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye DiseaseEfficacy Study of FK-506 and Cyclosporine in Vernal Keratoconjunctivits (VKC)Topical Cyclosporine Suspension for the Treatment of Brittle NailsEffect of Switching to Certican® in Viremia of Hepatitis C Virus in Adult Renal Allograft Recipients
P4844
Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signalingCrystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96-A resolutionCyclosporin A: a new drug in the field of canine dermatologyNF-kappaB is involved in the regulation of CD154 (CD40 ligand) expression in primary human T cellsGrowth factors and proliferation of cultured rat gingival cells in response to cyclosporin ACyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway.Kinetic Models of Cyclosporin A in Polar and Apolar Environments Reveal Multiple Congruent Conformational States.Cell cycle- and activation-dependent regulation of cyclosporin A-induced T cell apoptosis.The treatment of lupus with cyclosporin A.Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation.Differential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitorsCyclosporin as an oral corticosteroid sparing agent in stable asthma.MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatmentCyclosporin A inhibits the replication of diverse coronavirusesCyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transitionSelective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2Protein biomarkers of nephrotoxicity; a review and findings with cyclosporin A, a signal transduction kinase inhibitor and N-phenylanthranilic acid.Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity.Gene array identification of osteoclast genes: differential inhibition of osteoclastogenesis by cyclosporin A and granulocyte macrophage colony stimulating factor.Stimulation of interleukin-13 expression by human T-cell leukemia virus type 1 oncoprotein Tax via a dually active promoter element responsive to NF-kappaB and NFAT.Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A.Cyclosporin A-dependent downregulation of the Na+/Ca2+ exchanger expression.Interactions of cyclosporin a with breast cancer resistance protein.Treatment of neutral glycosphingolipid lysosomal storage diseases via inhibition of the ABC drug transporter, MDR1. Cyclosporin A can lower serum and liver globotriaosyl ceramide levels in the Fabry mouse model.Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan.The immunosuppressive drugs cyclosporin A and tacrolimus inhibit membrane depolarization-induced CREB transcriptional activity at the coactivator levelCyclosporin A induces proliferation in human gingival fibroblasts via induction of transforming growth factor-beta1.Specific inhibition of hepatitis C virus replication by cyclosporin A.Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein.The effect of cyclosporin A on the growth of human glioma cell lines.NFATc3 is required for intermittent hypoxia-induced hypertension.Cyclosporin A treatment increases rat soleus muscle oxidative capacities.Cyclosporin A increases basal intracellular calcium and calcium responses to endothelin and vasopressin in human coronary myocytes.Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition.Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release.FK506 inhibits Cl- secretion in airway epithelium via calcineurin-independent mechanism.Cellular and cytokine responses in the circulation and tissue reactions in the lung of rhesus monkeys (Macaca mulatta) pretreated with cyclosporin A and challenged with staphylococcal enterotoxin B.The mitochondrial permeability transition contributes to acute ethanol-induced apoptosis in rat hepatocytes.Important role of energy-dependent mitochondrial pathways in cultured rat cardiac myocyte apoptosis.Cyclosporin a promotes hair epithelial cell proliferation and modulates protein kinase C expression and translocation in hair epithelial cells.
P921
description
Chemical compound which is an ...... fungus Tolypocladium inflatum.
@en
Medikamentu immunodepresiboa, ...... usa saihesteko erabiltzen dena
@eu
chemesch Verbindung
@lb
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
name
Ciclosporin
@de
Ciclosporin
@hu
Ciclosporin
@vi
Ciclosporine
@nl
Ciklosporin
@nb
Ciklosporin
@sh
Ciklosporin
@sl
Ciklosporin
@sv
Siklosporiini
@fi
Siklosporina
@id
type
label
Ciclosporin
@de
Ciclosporin
@hu
Ciclosporin
@vi
Ciclosporine
@nl
Ciklosporin
@nb
Ciklosporin
@sh
Ciklosporin
@sl
Ciklosporin
@sv
Siklosporiini
@fi
Siklosporina
@id
altLabel
(R-[R*,R*-(E)])-cyclic(L-alany ...... cyl-L-valyl-N-methyl-L-leucyl)
@en
1,11-cyclo[L-alanyl-D-alanyl-N ...... yl-L-valyl-N-methyl-L-leucine]
@en
30-ethyl-33-[(4E)-1-hydroxy-2- ...... ,14,17,20,23,26,29,32-undecone
@cy
30-ethyl-33-[(4E)-1-hydroxy-2- ...... ,14,17,20,23,26,29,32-undecone
@en
Antibiotic S 7481F1
@cy
Antibiotic S 7481F1
@en
CsA
@cy
CsA
@en
CsA
@nn
CsA
@pl
prefLabel
Ciclosporin
@de
Ciclosporin
@hu
Ciclosporin
@vi
Ciclosporine
@nl
Ciklosporin
@nb
Ciklosporin
@sh
Ciklosporin
@sl
Ciklosporin
@sv
Siklosporiini
@fi
Siklosporina
@id