Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy.
about
A tumor-targeting p53 nanodelivery system limits chemoresistance to temozolomide prolonging survival in a mouse model of glioblastoma multiforme.Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicinCurrent understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme.Mitochondria-mediated apoptosis in mammals.Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 statusGenetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma.Metformin treatment reduces temozolomide resistance of glioblastoma cells.p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells.PRG3 induces Ras-dependent oncogenic cooperation in gliomas.Off and back-on again: a tumor suppressor's tale.CDH2 expression is of prognostic significance in glioma and predicts the efficacy of temozolomide therapy in patients with glioblastoma.
P2860
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P2860
Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Using a preclinical mouse mode ...... imize p53 restoration therapy.
@en
type
label
Using a preclinical mouse mode ...... imize p53 restoration therapy.
@en
prefLabel
Using a preclinical mouse mode ...... imize p53 restoration therapy.
@en
P2093
P2860
P356
P1476
Using a preclinical mouse mode ...... timize p53 restoration therapy
@en
P2093
Douglas Hanahan
Fanya Rostker
Gerard I Evan
Ksenya Shchors
Lamorna Brown Swigart
Mitchel S Berger
Natalya Lyubynska
Tarik Tihan
P2860
P304
P356
10.1073/PNAS.1219142110
P407
P577
2013-03-29T00:00:00Z