Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling.
about
In vitro models of aortic valve calcification: solidifying a systemAortic valve sclerosis in mice deficient in endothelial nitric oxide synthase.The role of valvular endothelial cell paracrine signaling and matrix elasticity on valvular interstitial cell activation.RUNX3 modulates hypoxia-induced endothelial-to-mesenchymal transition of human cardiac microvascular endothelial cells.Defining the role of fluid shear stress in the expression of early signaling markers for calcific aortic valve disease.Reciprocal interactions between mitral valve endothelial and interstitial cells reduce endothelial-to-mesenchymal transition and myofibroblastic activation.Endothelial-derived oxidative stress drives myofibroblastic activation and calcification of the aortic valveComparison of Mesenchymal Stem Cell Source Differentiation Toward Human Pediatric Aortic Valve Interstitial Cells within 3D Engineered Matrices.Valvular interstitial cells suppress calcification of valvular endothelial cells.3-Dimensional spatially organized PEG-based hydrogels for an aortic valve co-culture model.Application of hydrogels in heart valve tissue engineering.Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification.Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturationIdentification of side- and shear-dependent microRNAs regulating porcine aortic valve pathogenesis.Active tissue stiffness modulation controls valve interstitial cell phenotype and osteogenic potential in 3D culture.Heterogeneous susceptibility of valve endothelial cells to mesenchymal transformation in response to TNFα.Cadherin-11 expression patterns in heart valves associate with key functions during embryonic cushion formation, valve maturation and calcification.Three-dimensional printed trileaflet valve conduits using biological hydrogels and human valve interstitial cells.The living aortic valve: From molecules to function.Cardiac valve cells and their microenvironment--insights from in vitro studies.Shear-Sensitive Genes in Aortic Valve Endothelium.M1 macrophages promote aortic valve calcification mediated by microRNA-214/TWIST1 pathway in valvular interstitial cells.Current Challenges in Translating Tissue-Engineered Heart Valves.Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification.Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic ValvesDeveloping a Clinically Relevant Tissue Engineered Heart Valve-A Review of Current Approaches.Reproducible in vitro model for dystrophic calcification of cardiac valvular interstitial cells: insights into the mechanisms of calcific aortic valvular disease.Endothelial to mesenchymal transformation is induced by altered extracellular matrix in aortic valve endothelial cells.Elevated Serotonin Interacts with Angiotensin-II to Result in Altered Valve Interstitial Cell Contractility and Remodeling.ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells.Advances in Pathophysiology of Calcific Aortic Valve Disease Propose Novel Molecular Therapeutic Targets.Crystallinity of hydroxyapatite drives myofibroblastic activation and calcification in aortic valves.Effect of Side-Specific Valvular Shear Stress on the Content of Extracellular Matrix in Aortic Valves.
P2860
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P2860
Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Side-specific endothelial-depe ...... cs and nitric oxide signaling.
@ast
Side-specific endothelial-depe ...... cs and nitric oxide signaling.
@en
type
label
Side-specific endothelial-depe ...... cs and nitric oxide signaling.
@ast
Side-specific endothelial-depe ...... cs and nitric oxide signaling.
@en
prefLabel
Side-specific endothelial-depe ...... cs and nitric oxide signaling.
@ast
Side-specific endothelial-depe ...... cs and nitric oxide signaling.
@en
P2093
P2860
P1476
Side-specific endothelial-depe ...... cs and nitric oxide signaling.
@en
P2093
Adrian H Chester
Ismail El-Hamamsy
Jennifer Richards
Jonathan T Butcher
Magdi H Yacoub
Padmini Sarathchandra
Zubair Sarang
P2860
P304
P356
10.1016/J.AJPATH.2013.01.037
P407
P577
2013-03-13T00:00:00Z