A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen. - sprookjes - yvandenbroek - TriplyDB

A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen.

A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen.

http://www.wikidata.org/entity/Q36833617

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pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC)Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex 'knockout' mice Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP Molecular details of cAMP generation in mammalian cells: a tale of two systems Role of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulation Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosa Intracellular cAMP signaling by soluble adenylyl cyclase.Structural analysis of human soluble adenylyl cyclase and crystal structures of its nucleotide complexes-implications for cyclase catalysis and evolution Characterization of Plasmodium falciparum adenylyl cyclase-β and its role in erythrocytic stage parasites Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1 Structure-based development of novel adenylyl cyclase inhibitors Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase Decreased soluble adenylyl cyclase activity in cystic fibrosis is related to defective apical bicarbonate exchange and affects ciliary beat frequency regulation.Physiological carbon dioxide, bicarbonate, and pH sensing Identification of a haem domain in human soluble adenylate cyclase.Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase Soluble adenylyl cyclase in health and disease.Pivotal role of extended linker 2 in the activation of Gα by G protein-coupled receptor.Requirement of cAMP signaling for Schwann cell differentiation restricts the onset of myelination Role of soluble adenylyl cyclase in the heart.Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth.Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor Pharmacological distinction between soluble and transmembrane adenylyl cyclases.Established and potential physiological roles of bicarbonate-sensing soluble adenylyl cyclase (sAC) in aquatic animals.Biological roles of cAMP: variations on a theme in the different kingdoms of life.Soluble adenylyl cyclase of sea urchin spermatozoa.Expression, purification, crystallization and preliminary X-ray diffraction analysis of a mammalian type 10 adenylyl cyclase.Characterization of a novel signal transducer element intrinsic to class IIIa/b adenylate cyclases and guanylate cyclases.International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Protein Kinase A Governs Oxidative Phosphorylation Kinetics and Oxidant Emitting Potential at Complex I.Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction.Structures, substrates, and regulators of Mammalian sirtuins - opportunities and challenges for drug development.Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells Functional Significance of the Adcy10-Dependent Intracellular cAMP Compartments.

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P2860

A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen.

http://www.wikidata.org/entity/Q36833617

description

2005 nî lūn-bûn

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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2005年论文

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2005年论文

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name

A novel mechanism for adenylyl ...... omplex with catechol estrogen.

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type

label

A novel mechanism for adenylyl ...... omplex with catechol estrogen.

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prefLabel

A novel mechanism for adenylyl ...... omplex with catechol estrogen.

@en

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A novel mechanism for adenylyl ...... omplex with catechol estrogen.

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Austin B Capper

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Clemens Steegborn

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Hao Wu

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Kenneth C Hess

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Ronald Taussig

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Tatiana N Litvin

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P2860

Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals

Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

Two-metal-Ion catalysis in adenylyl cyclase

Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state.

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

Structure of the adenylyl cyclase catalytic core

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

Raster3D Version 2.0. A program for photorealistic molecular graphics

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280

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