Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
about
Malate and fumarate extend lifespan in Caenorhabditis elegansThe importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current stateMitophagy plays a central role in mitochondrial ageingThe Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative DiseasesReprogramming of energy metabolism as a driver of agingAntioxidant Supplementation in the Treatment of Aging-Associated DiseasesBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesConnecting proline metabolism and signaling pathways in plant senescenceSestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose TissueAntioxidant responses and cellular adjustments to oxidative stressProline metabolism and cancer: emerging links to glutamine and collagenMitohormesisNew insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heartMitochondrial proteostasis in the control of aging and longevityFolliculin regulates ampk-dependent autophagy and metabolic stress survivalBranched-chain amino acid catabolism is a conserved regulator of physiological ageing.Sexual Preferences in Nutrient Utilization Regulate Oxygen Consumption and Reactive Oxygen Species Generation in Schistosoma mansoni: Potential Implications for Parasite Redox BiologyStructures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding siteMitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!An evidence-based approach to identify aging-related genes in Caenorhabditis elegansROS function in redox signaling and oxidative stressPhysiological roles of mitochondrial reactive oxygen speciesRole of sirtuins in lifespan regulation is linked to methylation of nicotinamide.Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.The determination and analysis of site-specific rates of mitochondrial reactive oxygen species production.Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation.The mitochondrial unfolded protein response and increased longevity: cause, consequence, or correlation?A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegansMetformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2D-beta-hydroxybutyrate extends lifespan in C. elegans.Proline biosynthesis is required for endoplasmic reticulum stress tolerance in Saccharomyces cerevisiae.The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.The paradox of mitochondrial dysfunction and extended longevity.The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegansProline metabolism increases katG expression and oxidative stress resistance in Escherichia coli.AMPK at the nexus of energetics and aging.Extension of life span by impaired glucose metabolism in Caenorhabditis elegans is accompanied by structural rearrangements of the transcriptomic network.
P2860
Q21133638-34624FAB-1052-47DE-B583-978779DA34DBQ26741668-D5732CA4-6F16-4061-B0CF-4D4079E769C9Q26746323-9A65B817-EB21-4CF3-81FC-3468F85FFE4FQ26750137-B27486CC-D6F2-4020-B84C-E8E2379F2676Q26766053-7358D812-283B-4C99-967D-C3F602B81571Q26768165-86B96176-1E0D-4D8A-AC11-85994ABCA828Q26777407-EDC99715-34A3-4F17-B3C3-781D84244048Q26782776-00A52D3F-A5C5-47C3-9D1B-58BE63D157ECQ26800174-3EBA351C-6426-48C9-9A1F-DE08C5F77378Q26800229-DB00CB93-5010-44E9-8FCE-DAB1D0DE99F2Q26861005-719D529F-4B37-4438-889D-52E237391E79Q26862860-609C9D5D-4208-4D18-8F65-BB19B2071EFAQ26865574-5F1A7D20-8E0C-4753-A1D0-45667807154CQ26999871-2CB93E92-21CA-45F0-932D-CE9181E8894EQ27316476-8B71479A-D8E0-458E-A1C9-9DBF1FBD7F8FQ27342729-8926E001-4F12-4A90-8A2C-90B14E6A27FEQ27468987-2C96354E-15E9-4A8B-9F4C-D90393DE4B83Q27681821-FF7EED19-402E-4A86-B885-B1D7FBF59223Q28068299-47DC5062-1F68-460F-9226-7D8675D9AC2BQ28649457-150BBB46-5542-4AC1-A7CD-656BAD5D4EE0Q29615229-59F14AE9-7BD6-4362-87BD-D6A989953C32Q29620297-D47783EC-AA89-4B55-805B-2AACEB0C5A80Q30582056-CAC1C842-6DA0-4BB9-AA29-E2085825A57FQ30625412-AEA50F34-0D47-4590-8943-F3D9E58CD488Q33558886-91E13B1B-6534-44A4-95B6-139B5C63DA3DQ33668586-86CAF17E-A4F4-4C88-BFB4-0D5F4102066DQ33676890-12948A51-545D-4A2D-9AD7-D02CFDF293E7Q33685916-64B90A78-0678-4AC0-BB99-CEEE069B4EA5Q33723766-9DD3FD07-0038-49BE-BCA8-5BD20F3A915DQ33729188-A39F0DF8-CF7B-43E2-A937-04FBE2368F60Q33790225-4A67F463-1BFD-4DE6-B19A-7F8D422F5274Q34217599-C610C79C-495D-4263-815F-277044195765Q34283514-2D868721-676B-4F44-861C-422B3B076993Q34358623-9AC7BDA3-6C91-43B8-9EA7-142BA76A982EQ34407440-76D525D1-D9C4-49AD-BD4D-0F7073C86EEFQ34413560-FD286949-937A-47D3-8E92-C970EBD45D5FQ34419483-D8B01A45-0C37-49DA-A36D-9B39B158B189Q34853615-8B91EBFE-6AF9-425D-9866-A388275B560AQ34871517-D89C46B8-F354-4E72-813D-3EA43EEB7617Q35035607-C2B841E3-194F-4A55-A4BE-476F304EB808
P2860
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Impaired insulin/IGF1 signalin ...... induce a transient ROS signal
@en
type
label
Impaired insulin/IGF1 signalin ...... induce a transient ROS signal
@en
prefLabel
Impaired insulin/IGF1 signalin ...... induce a transient ROS signal
@en
P2860
P50
P1433
P1476
Impaired insulin/IGF1 signalin ...... induce a transient ROS signal
@en
P2093
Gregor Beuster
Steffen Priebe
P2860
P304
P356
10.1016/J.CMET.2012.02.013
P50
P577
2012-04-01T00:00:00Z