CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium.
about
A four-marker signature of TNF-RII, TGF-α, TIMP-1 and CRP is prognostic of worse survival in high-risk surgically resected melanomaMacroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerancePositive and negative selection of the T cell repertoire: what thymocytes see (and don't see)C-reactive protein: structural biology and host defense function.Lymphostromal interactions in thymic development and function.Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation.Thymic selection revisited: how essential is it?Self-representation in the thymus: an extended view.Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection.C-reactive protein in vulnerable coronary plaques.Natural regulatory T cells and self-tolerance.Contrasting models of promiscuous gene expression by thymic epitheliumPerinatal blockade of b7-1 and b7-2 inhibits clonal deletion of highly pathogenic autoreactive T cells.Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.Establishment and functioning of intrathymic microenvironments.Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentationThymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction.Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins.Absence of some common organ-specific and non-organ-specific autoimmunity in autoimmune polyendocrinopathy candidiasis ectodermal dystrophyAdvances in type I diabetes associated tolerance mechanisms.Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes.Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue.Thymic epithelial cells: antigen presenting cells that regulate T cell repertoire and tolerance development.Medullary thymic epithelial cells, the indispensable player in central tolerance.The rationale of vectored gene-fusion vaccines against cancer: evolving strategies and latest evidence.Medullary thymic epithelium: a mosaic of epithelial "self"?T-cell tolerance: central and peripheralDynamic changes during the immune response in T cell-antigen-presenting cell clusters isolated from lymph nodes.The thymic medulla: a unique microenvironment for intercellular self-antigen transferCompartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen.Proceedings of the conference "Lymphocyte development, tolerance and autoimmunity: solved and open questions", held at the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, on May 12, 2011 (Wrocław, PolanIndirect presentation in the thymus limits naïve and regulatory T cell differentiation by promoting deletion of self-reactive thymocytes.Negative selection of the T-cell repertoire: where and when does it occur?Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.
P2860
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P2860
CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
CD4 T cell tolerance to human ...... y medullary thymic epithelium.
@en
type
label
CD4 T cell tolerance to human ...... y medullary thymic epithelium.
@en
prefLabel
CD4 T cell tolerance to human ...... y medullary thymic epithelium.
@en
P2093
P2860
P356
P1476
CD4 T cell tolerance to human ...... y medullary thymic epithelium.
@en
P2093
P2860
P356
10.1084/JEM.188.1.5
P407
P577
1998-07-01T00:00:00Z