Blood-brain barrier transport of therapeutics via receptor-mediation - sprookjes - yvandenbroek - TriplyDB

Blood-brain barrier transport of therapeutics via receptor-mediation

Blood-brain barrier transport of therapeutics via receptor-mediation

http://www.wikidata.org/entity/Q36874295

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Nanoparticles for brain drug delivery Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2 Systemic delivery to central nervous system by engineered PLGA nanoparticles Development of targeted therapies in treatment of glioblastoma Dendrimer advances for the central nervous system delivery of therapeutics CD133, Selectively Targeting the Root of Cancer Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier.The molecular constituents of the blood-brain barrier Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro TNAP and EHD1 are over-expressed in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties Targeting therapeutics across the blood brain barrier (BBB), prerequisite towards thrombolytic therapy for cerebrovascular disorders-an overview and advancements Drug delivery systems, CNS protection, and the blood brain barrier Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound.Combinatorial approaches for the identification of brain drug delivery targets.Identification of peptide ligands for targeting to the blood-brain barrier Transferrin-appended PEGylated nanoparticles for temozolomide delivery to brain: in vitro characterisation.Identifying blood-brain-barrier selective single-chain antibody fragments.A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody.Copolymers of poly(lactic acid) and D-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicines: versatile multifunctional platforms for cancer diagnosis and therapy.Imaging of cells and nanoparticles: implications for drug delivery to the brain.Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid Imaging the L-type amino acid transporter-1 (LAT1) with Zr-89 immunoPET Binding, transcytosis and biodistribution of anti-PECAM-1 iron oxide nanoparticles for brain-targeted delivery.A human blood-brain barrier transcytosis assay reveals antibody transcytosis influenced by pH-dependent receptor binding.Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry Assessing the transport of receptor-mediated drug-delivery devices across cellular monolayers The biology of brain metastases-translation to new therapies Evaluation of Nonferrous Metals as Potential In Vivo Tracers of Transferrin-Based Therapeutics.An RNA alternative to human transferrin: a new tool for targeting human cells.Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core.Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells.Mass spectrometry-guided optimization and characterization of a biologically active transferrin-lysozyme model drug conjugate.An adsorption chromatography assay to probe bulk particle transport through hydrogels.A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells.Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium.Pharmacokinetics of recombinant bifunctional fusion proteins.Drug delivery to brain tumors.Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier.New strategies to deliver anticancer drugs to brain tumors.

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P2860

Blood-brain barrier transport of therapeutics via receptor-mediation

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High transcytosis of melanotransferrin (P97) across the blood-brain barrier

Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway

Tyrosine hydroxylase and Parkinson's disease

Blood-brain barrier transcytosis of insulin in developing rabbits

Immunogens consisting of oligosaccharides from the capsule of Haemophilus influenzae type b coupled to diphtheria toxoid or the toxin protein CRM197

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

Selection of phage-displayed llama single-domain antibodies that transmigrate across human blood-brain barrier endothelium.

Efficient cancer therapy with a nanobody-based conjugate.

Mining a yeast library for brain endothelial cell-binding antibodies.

Vector-mediated delivery of 125I-labeled beta-amyloid peptide A beta 1-40 through the blood-brain barrier and binding to Alzheimer disease amyloid of the A beta 1-40/vector complex.

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