Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts.
about
PrimPol, an archaic primase/polymerase operating in human cellsMinireview: DNA replication in plant mitochondriaA rolling circle replication mechanism produces multimeric lariats of mitochondrial DNA in Caenorhabditis elegansIn vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replicationMitochondrial DNA replication: a PrimPol perspective.Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease.Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondriaRNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial EncephalomyopathyMitochondrial transcription terminator family members mTTF and mTerf5 have opposing roles in coordination of mtDNA synthesis.Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.The inversion of the Control Region in three mitogenomes provides further evidence for an asymmetric model of vertebrate mtDNA replication.Evolution of the metazoan mitochondrial replicase.MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in MitochondriaPrimer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication.Low doses of ultraviolet radiation and oxidative damage induce dramatic accumulation of mitochondrial DNA replication intermediates, fork regression, and replication initiation shiftNucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA.Mitochondrial transcription termination factor 1 directs polar replication fork pausing.Animal Mitochondrial DNA Replication.Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria.POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.Replicating animal mitochondrial DNA.Underlying role of mitochondrial mutagenesis in the pathogenesis of a disease and current approaches for translational research.Mitochondrial DNA in innate immune responses and inflammatory pathology.Cellular and population level processes influence the rate, accumulation and observed frequency of inherited and somatic mtDNA mutations.R-loops and initiation of DNA replication in human cells: a missing link?Length heterogeneity at conserved sequence block 2 in human mitochondrial DNA acts as a rheostat for RNA polymerase POLRMT activity.Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase.PrimPol is required for replication reinitiation after mtDNA damage.Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase.Endonuclease G promotes mitochondrial genome cleavage and replication.Suppression of mitochondrial transcription initiation complexes changes the balance of replication intermediates of mitochondrial DNA and reduces 7S DNA in cultured human cells.Transcript availability dictates the balance between strand-asynchronous and strand-coupled mitochondrial DNA replicationMitochondrial DNA replication in mammalian cells: overview of the pathway
P2860
Q24339480-FD936DA4-4BF0-42BF-A955-4378A8CD2014Q26991547-4A8CB2BC-23A4-4889-BC08-3175E823F425Q27311508-A5BF6DE2-0297-4005-A783-B1A7CFA739BBQ28542495-9973521E-67CB-4AA6-8B8C-330B9326659DQ33560901-11A985A5-5D49-4F44-BB02-3CE8761CE874Q34427479-76202E8B-D31B-4856-AB71-6C95A6DCA36AQ34427946-9C617E78-56F0-4FE8-A8A7-BEA0641E9B5DQ34481585-1F7C99EC-27C2-4815-A77A-11D4BD42386BQ34998342-4BBB27E3-027E-40AC-846A-75A9F964A703Q35152167-91C10481-8E38-40FD-8B00-52B252DB47DAQ35288143-C7FC64AE-3C3B-46E0-8EBA-08C44DD385ADQ35569785-B2899187-72F7-4242-BE33-4CCA596E55AEQ35892524-6146A676-4F94-4764-9D8C-E8B5B50FB55DQ35910060-506C6C55-7D6F-446D-B7B3-3DD72A268444Q36274506-3225024C-7CBE-4345-9597-F4BF87D43F76Q36282442-2145BA2D-4A1A-4C2F-9086-7A6187198750Q37076313-1A22156A-806B-4472-B4E4-FEBDDFD60AA3Q37135534-459E5EC3-CB63-4AB5-AAC0-5A04DFA8B6B3Q37142690-7BC58DBF-376F-4EC0-8D3D-07AEB60C8CDEQ37155771-7EAC7904-3A73-4105-AF39-E1840D8D9425Q38153032-1D8DF1A4-95E1-41E3-8CBD-161DAF86CCC0Q39000027-9CDFC0BC-7DF2-4751-A9EF-A34D54D38AB0Q39231387-38912119-E9D3-4291-B23E-194AAFF9E4A2Q39315783-C0CFC409-F836-4834-87D8-927DA7DB1E7DQ40009006-75E7F56A-7664-492B-8781-81C7D303A58DQ41117429-89C5327A-2313-4DD0-888F-FE928EA48316Q41626623-7C19DE7B-5822-464B-AF89-7240848F370DQ48123412-89DBAF77-5E14-4DDF-8296-B3CB348FF8C8Q50061696-6DDDBBB7-2B62-414B-A246-9BED8E85F10AQ52714605-94CD2790-7367-4F07-A4C1-DCE2899C143DQ53635378-E1E13039-B758-4B07-A972-1C8290D2C466Q57752905-204BF44F-5B23-486E-BDA0-C2E63609C85EQ57753617-57248714-2EE8-4A66-9D30-046230861A7D
P2860
Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Mitochondrial DNA replication ...... tion of processed transcripts.
@en
type
label
Mitochondrial DNA replication ...... tion of processed transcripts.
@en
prefLabel
Mitochondrial DNA replication ...... tion of processed transcripts.
@en
P2093
P2860
P356
P1476
Mitochondrial DNA replication ...... tion of processed transcripts.
@en
P2093
Aurelio Reyes
Howard T Jacobs
Lawrence Kazak
Stuart R Wood
Takehiro Yasukawa
P2860
P304
P356
10.1093/NAR/GKT196
P407
P50
P577
2013-04-16T00:00:00Z