Targeting the human cancer pathway protein interaction network by structural genomics.
about
Cancer systems biology: a network modeling perspectiveEvolution and applications of plant pathway resources and databasesCrystal structure of human retinoblastoma binding protein 9NMR structure of F-actin-binding domain of Arg/Abl2 from Homo sapiensSolution NMR structure of the ARID domain of human AT-rich interactive domain-containing protein 3A: A human cancer protein interaction network targetThe Structure of Vimentin Linker 1 and Rod 1B Domains Characterized by Site-directed Spin-labeling Electron Paramagnetic Resonance (SDSL-EPR) and X-ray CrystallographyHuman Cyclin-dependent Kinase 2-associated Protein 1 (CDK2AP1) Is Dimeric in Its Disulfide-reduced State, with Natively Disordered N-terminal RegionHuman cancer protein-protein interaction network: a structural perspectiveOverexpression of the catalytically impaired Taspase1 T234V or Taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cellsCancer missense mutations alter binding properties of proteins and their interaction networksQuantification of the impact of PSI:Biology according to the annotations of the determined structuresOutcome of a workshop on applications of protein models in biomedical researchThe RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRASAssessment of template-based protein structure predictions in CASP10Advances in protein NMR provided by the NIGMS Protein Structure Initiative: impact on drug discovery.The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium.Preparation of protein samples for NMR structure, function, and small-molecule screening studiesThe Protein Structure Initiative: achievements and visions for the future.The Protein Structure Initiative Structural Biology Knowledgebase Technology Portal: a structural biology web resource.Creating a community resource for protein science.A computational framework for boosting confidence in high-throughput protein-protein interaction datasetsEfficient condensed-phase production of perdeuterated soluble and membrane proteinsExploring a structural protein-drug interactome for new therapeutics in lung cancerComputational tools for the interactive exploration of proteomic and structural data.BioDrugScreen: a computational drug design resource for ranking molecules docked to the human proteomeDocking Small Molecules to Predicted Off-Targets of the Cancer Drug Erlotinib Leads to Inhibitors of Lung Cancer Cell Proliferation with Suitable In vitro Pharmacokinetic Properties.Engineering of a wheat germ expression system to provide compatibility with a high throughput pET-based cloning platform.Kinetic rate constant prediction supports the conformational selection mechanism of protein binding.Polypeptide backbone, C(β) and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectiniWRAP: An interface threading approach with application to prediction of cancer-related protein-protein interactionsSolution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development.Communication routes in ARID domains between distal residues in helix 5 and the DNA-binding loops.Solution structure of the free Zα domain of human DLM-1 (ZBP1/DAI), a Z-DNA binding domainConstructing the angiome: a global angiogenesis protein interaction network.Human retinoblastoma binding protein 9, a serine hydrolase implicated in pancreatic cancersSolution NMR structures of immunoglobulin-like domains 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the Human Cancer Protein Interaction Network.Computational large-scale mapping of protein-protein interactions using structural complexes.pathDIP: an annotated resource for known and predicted human gene-pathway associations and pathway enrichment analysis.PDID: database of molecular-level putative protein-drug interactions in the structural human proteome.
P2860
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P2860
Targeting the human cancer pathway protein interaction network by structural genomics.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Targeting the human cancer pathway protein interaction network by structural genomics.
@en
type
label
Targeting the human cancer pathway protein interaction network by structural genomics.
@en
prefLabel
Targeting the human cancer pathway protein interaction network by structural genomics.
@en
P2093
P2860
P1476
Targeting the human cancer pathway protein interaction network by structural genomics.
@en
P2093
Dehua Hang
Liang Tong
Long Jason Lu
Yuanpeng Janet Huang
P2860
P304
P356
10.1074/MCP.M700550-MCP200
P577
2008-05-18T00:00:00Z