Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1).
about
Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusInterleukin-27: balancing protective and pathological immunityInterleukin-27 in T cell immunityEmerging roles of Egr2 and Egr3 in the control of systemic autoimmunityThe MRL/lpr mouse strain as a model for neuropsychiatric systemic lupus erythematosus.WSX1 expression in tumors induces immune tolerance via suppression of effector immune cells.IL-27 Regulates IL-18 binding protein in skin resident cellsTGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responsesIL-27-induced modulation of autoimmunity and its therapeutic potential.The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses.An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunctionComplement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation.The dysregulation of cytokine networks in systemic lupus erythematosus.Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination.Interleukin 27: a double-edged sword for offense and defense.Therapeutic potential of IL-27 in systemic lupus erythematosus.Regulatory T-cell-associated cytokines in systemic lupus erythematosus.IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.Keratoacanthoma accompanied by multiple lung squamous cell carcinomas developing in a renal transplant recipient.Human interleukin-27: wide individual variation in plasma levels and complex inter-relationships with interleukin-17A.Overexpression of Epstein-Barr virus-induced gene 3 protein (EBI3) in MRL/lpr mice suppresses their lupus nephritis by activating regulatory T cells.Systemic Lupus Erythematosus Accompanied by Psoriasis Induces IL-27-Producing Cells in Both Affected Areas of the Skin.Decreased serum interleukin 27 in Brazilian systemic lupus erythematosus patients.IL-27 is elevated in acute lung injury and mediates inflammation.T cell-specific overexpression of interleukin-27 receptor α subunit (WSX-1) prevents spontaneous skin inflammation in MRL/lpr mice.Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl‑2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice.
P2860
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P2860
Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1).
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Amelioration of human lupus-li ...... kin 27 receptor alpha (WSX-1).
@en
type
label
Amelioration of human lupus-li ...... kin 27 receptor alpha (WSX-1).
@en
prefLabel
Amelioration of human lupus-li ...... kin 27 receptor alpha (WSX-1).
@en
P2093
P2860
P356
P1476
Amelioration of human lupus-li ...... kin 27 receptor alpha (WSX-1).
@en
P2093
Akahoshi M
Masutani K
Nakashima H
Sadanaga A
Sugiyama N
P2860
P304
P356
10.1136/ARD.2007.077537
P407
P577
2007-12-18T00:00:00Z