Conserved C-terminal threonine of hepatitis C virus NS3 regulates autoproteolysis and prevents product inhibition.
about
Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 HelicaseHepatitis C: recent successes and continuing challenges in the development of improved treatment modalitiesDiscovery of an allosteric mechanism for the regulation of HCV NS3 protein functionNew details of HCV NS3/4A proteinase functionality revealed by a high-throughput cleavage assayIncreasing rate of cleavage at boundary between non-structural proteins 4B and 5A inhibits replication of hepatitis C virus.Host proteins associated with Hepatitis C virus encoded NS4A.Genetic complementation of hepatitis C virus nonstructural protein functions associated with replication exhibits requirements that differ from those for virion assembly.A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animalsConstruction of eukaryotic expression plasmid containing HCV NS3 segment and protein expression in human HL-7702 hepatocytes.Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations.
P2860
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P2860
Conserved C-terminal threonine of hepatitis C virus NS3 regulates autoproteolysis and prevents product inhibition.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Conserved C-terminal threonine ...... d prevents product inhibition.
@en
type
label
Conserved C-terminal threonine ...... d prevents product inhibition.
@en
prefLabel
Conserved C-terminal threonine ...... d prevents product inhibition.
@en
P2093
P2860
P1433
P1476
Conserved C-terminal threonine ...... d prevents product inhibition.
@en
P2093
Bruce A Malcolm
Frederick C Lahser
Jacquelyn Wright-Minogue
MinKyung Yi
Patricia C Weber
Stanley M Lemon
Wenyan Wang
P2860
P304
P356
10.1128/JVI.78.2.700-709.2004
P407
P577
2004-01-01T00:00:00Z