Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain
about
Optimized purification of a heterodimeric ABC transporter in a highly stable form amenable to 2-D crystallizationCurcumin and genistein: the combined effects on disease-associated CFTR mutants and their clinical implicationsRegulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions.Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domainApplications of proteomic technologies for understanding the premature proteolysis of CFTR.Molecular modelling and molecular dynamics of CFTR.Hot on the trail of TRP channel structure.Gating of the CFTR Cl- channel by ATP-driven nucleotide-binding domain dimerisation.Cystic fibrosis transmembrane conductance regulator (ABCC7) structureFunctional architecture of the CFTR chloride channel.The biophysics, biochemistry and physiology of CFTR.Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore.Alternating access to the transmembrane domain of the ATP-binding cassette protein cystic fibrosis transmembrane conductance regulator (ABCC7).On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator.Structural models of CFTR-AMPK and CFTR-PKA interactions: R-domain flexibility is a key factor in CFTR regulation.Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel.Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.Structural mechanisms of CFTR function and dysfunction.ATP hydrolysis-dependent asymmetry of the conformation of CFTR channel pore.
P2860
Q28478129-5122C6B4-E294-4451-BB39-361544111284Q28830793-437F3A95-2B9E-4D7A-9E3C-393CF08053F0Q30557795-458367BC-DDAB-457B-BD8D-5C3AFA499DE8Q33418541-7B5D18B6-4E83-4464-87DC-86D590C1044CQ34076025-346A78AF-F408-405A-B9B4-B27584104471Q36158194-C3954C15-B852-4443-8FA2-57A32D116F00Q37399785-CD938905-5FCB-4A27-86E7-E5CEE7A080D8Q37427078-BC412D8E-69C6-4FFD-92A9-D1216CBDF716Q38078917-0C983A2E-5F1F-40B6-93F9-9C956EE0D772Q38171539-BE241E7C-7783-4F3E-B815-F3D1DC982BBAQ38972427-64258C2F-BC9E-41B6-AE47-F49E1078DC65Q39289067-47ECEB80-BF7B-41F5-82BD-507728C3BF05Q39401986-FDCF8CEE-445D-4809-BDE9-3BA8A5E77CC0Q40023091-93B55EE2-53B6-4C37-8985-DB26A3F0CFB1Q40098219-2341578F-4039-4AFE-B384-54A6ACC95215Q42854492-294E637A-62D4-4FBE-9E82-FB11314B0C71Q51766345-2577D72F-0211-439E-8AE1-26AEFAE92788Q51766349-F3027F6F-2996-4D23-91D6-28BAC8312338Q52629670-903F4D67-111A-4E9F-815C-9FF8F069E08EQ54211454-3DA4464B-AF90-4FD0-9C16-528319AD7FED
P2860
Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Three-dimensional reconstructi ...... putative transmembrane domain
@en
type
label
Three-dimensional reconstructi ...... putative transmembrane domain
@en
prefLabel
Three-dimensional reconstructi ...... putative transmembrane domain
@en
P2093
P2860
P356
P1476
Three-dimensional reconstructi ...... putative transmembrane domain
@en
P2093
Hiroyasu Shimizu
Kazuhiro Mio
Muneyo Mio
Toshihiko Ogura
Tzyh-Chang Hwang
Yoshiro Sohma
P2860
P304
30300-30310
P356
10.1074/JBC.M803185200
P407
P50
P577
2008-08-22T00:00:00Z