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Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cellsTargeting of alpha-v integrins reduces malignancy of bladder carcinomaVicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activitiesAbituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients withKRASwild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trialIntegrin alphaV is necessary for gastrulation movements that regulate vertebrate body asymmetry.Integrins as "functional hubs" in the regulation of pathological angiogenesisProgrammable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds.Safety, tolerability, and pharmacokinetics of the novel αv-integrin antibody EMD 525797 (DI17E6) in healthy subjects after ascending single intravenous doses.Role of RGD-containing ligands in targeting cellular integrins: Applications for ovarian cancer virotherapy (Review)Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.Characterization and evaluation of (64)Cu-labeled A20FMDV2 conjugates for imaging the integrin αvβ 6Development of a chimeric recombinant disintegrin as a cost-effective anti-cancer agent with promising translational potential.Mechanism for laser-induced neovascularization in rat choroid: accumulation of integrin α chain-positive cells and their ligands.Integrin αv expression is required for the acquisition of a metastatic stem/progenitor cell phenotype in human prostate cancer.Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis.aV integrins and TGF-β-induced EMT: a circle of regulationAntibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease.Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition.Expression of αV-integrins in uterine serous papillary carcinomas; implications for targeted therapy with intetumumab (CNTO 95), a fully human antagonist anti-αV-integrin antibodyThe antitumor activity of a doxorubicin loaded, iRGD-modified sterically-stabilized liposome on B16-F10 melanoma cells: in vitro and in vivo evaluationInstant immunity through chemically programmable vaccination and covalent self-assembly.Nucleoside diphosphate kinase/Nm23 and Epstein-Barr virus.The roles of αV integrins in lens EMT and posterior capsular opacification.The extracellular matrix in digestive cancerMultifunctional adamantane derivatives as new scaffolds for the multipresentation of bioactive peptides.β1,6-branched complex-type N-glycans affect FAK signaling in metastatic melanoma cells.Integrin trafficking and tumor progression.Prostate cancer cells home to bone using a novel in vivo model: modulation by the integrin antagonist GLPG0187.Studies on primary uveal and cutaneous melanoma cell interaction with vitronectin.Dual inhibition of αV integrins and Src kinase activity as a combination therapy strategy for colorectal cancer.A novel PET tracer for the imaging of αvβ3 and αvβ5 integrins in experimental breast cancer bone metastases.Proteinase-activated receptors 1 and 2 regulate invasive behavior of human melanoma cells via activation of protein kinase D1.Development of isoxazoline-containing peptidomimetics as dual αvβ3 and α5β1 integrin ligands.Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study.Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor modelReduced growth and integrin expression of prostate cells cultured with lycopene, vitamin E and fish oil in vitro.Integrin receptors on tumor cells facilitate NK cell-mediated antibody-dependent cytotoxicity.Alphav integrins lead the way for colorectal metastases.Glycosaminoglycan chains from alpha5beta1 integrin are involved in fibronectin-dependent cell migration.Overexpression of integrin αv correlates with poor prognosis in colorectal cancer.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Alpha-v integrins as therapeutic targets in oncology.
@en
Alpha-v integrins as therapeutic targets in oncology.
@nl
type
label
Alpha-v integrins as therapeutic targets in oncology.
@en
Alpha-v integrins as therapeutic targets in oncology.
@nl
prefLabel
Alpha-v integrins as therapeutic targets in oncology.
@en
Alpha-v integrins as therapeutic targets in oncology.
@nl
P2093
P2860
P1433
P1476
Alpha-v integrins as therapeutic targets in oncology
@en
P2093
Hugh M Davis
Jeffrey A Nemeth
Marian T Nakada
Michael S Gordon
Robert A Beckman
Robert Corringham
Uma Prabhakar
Zhihui Lang
P2860
P304
P356
10.1080/07357900701522638
P577
2007-10-01T00:00:00Z