Glycan antagonists and inhibitors: a fount for drug discovery. - sprookjes - yvandenbroek - TriplyDB

Glycan antagonists and inhibitors: a fount for drug discovery.

Glycan antagonists and inhibitors: a fount for drug discovery.

http://www.wikidata.org/entity/Q37027396

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Glycotherapy: new advances inspire a reemergence of glycans in medicine Deoxygenated Disaccharide Analogs as Specific Inhibitors of 1-4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate Advancement of Sialyltransferase Inhibitors: Therapeutic Challenges and Opportunities Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1.Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus.Therapeutic approaches for lysosomal storage diseases Liposomes modified by carbohydrate ligands can target B cells for the treatment of B-cell lymphomas.Bioorthogonal chemical reporter methodology for visualization, isolation and analysis of glycoconjugates Stereoselective assembly of complex oligosaccharides using anomeric sulfonium ions as glycosyl donors 5-thiomannosides block the biosynthesis of dolichol-linked oligosaccharides and mimic class I congenital disorders of glycosylation Role of glycosaminoglycans in infectious disease Circulating N-Linked Glycoprotein Side-Chain Biomarker, Rosuvastatin Therapy, and Incident Cardiovascular Disease: An Analysis From the JUPITER Trial.Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research.Adaptive immune activation: glycosylation does matter.Emerging drugs for lysosomal storage diseases.Recent advances in the understanding of biological implications and modulation methodologies of monoclonal antibody N-linked high mannose glycans.Sialylation: an Avenue to Target Cancer Cells.Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction.Drug-Mediated Regulation of Glycosaminoglycan Biosynthesis.A sensor of protein O-glycosylation based on sequential processing in the Golgi apparatus.Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome.A universal flow cytometry assay for screening carbohydrate-active enzymes using glycan microspheres.Human disease glycomics: technology advances enabling protein glycosylation analysis - part 1.

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P2860

Glycan antagonists and inhibitors: a fount for drug discovery.

http://www.wikidata.org/entity/Q37027396

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

Glycan antagonists and inhibitors: a fount for drug discovery.

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Glycan antagonists and inhibitors: a fount for drug discovery.

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Glycan antagonists and inhibitors: a fount for drug discovery.

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Glycan antagonists and inhibitors: a fount for drug discovery.

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Glycan antagonists and inhibitors: a fount for drug discovery.

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Glycan antagonists and inhibitors: a fount for drug discovery.

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Critical Reviews in Biochemistry and Molecular Biology

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Glycan antagonists and inhibitors: a fount for drug discovery.

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Brett E Crawford

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Jeffrey D Esko

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Jillian R Brown

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P2860

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression

Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.

Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins

The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

Keratan sulfate biosynthesis

Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

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