BET proteins promote efficient murine leukemia virus integration at transcription start sites. - sprookjes - yvandenbroek - TriplyDB

BET proteins promote efficient murine leukemia virus integration at transcription start sites.

BET proteins promote efficient murine leukemia virus integration at transcription start sites.

http://www.wikidata.org/entity/Q37031911

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Applications of DNA integrating elements: Facing the bias bully Impact of Chromatin on HIV Replication Multifunctional facets of retrovirus integrase Foamy virus vectors for HIV gene therapy The bromodomain: from epigenome reader to druggable target Nuclear trafficking of retroviral RNAs and Gag proteins during late steps of replication Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration.Retroviral Integrase: Then and Now Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection Retroviral DNA Integration Structural and sequencing analysis of local target DNA recognition by MLV integrase.Enhancers are major targets for murine leukemia virus vector integration Concise review: lessons learned from clinical trials of gene therapy in monogenic immunodeficiency diseases.Epigenetic control of mobile DNA as an interface between experience and genome change.Structural basis for spumavirus GAG tethering to chromatin Chemical probes targeting epigenetic proteins: Applications beyond oncology.Genome-wide analysis of alpharetroviral integration in human hematopoietic stem/progenitor cells.Novel principles of gamma-retroviral insertional transcription activation in murine leukemia virus-induced end-stage tumors.Serial number tagging reveals a prominent sequence preference of retrotransposon integration Molecular mechanisms of retroviral integration site selection.The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites.The N-terminus of murine leukaemia virus p12 protein is required for mature core stability.Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.Intasome architecture and chromatin density modulate retroviral integration into nucleosome Retroviral DNA Transposition: Themes and Variations Key determinants of target DNA recognition by retroviral intasomes.DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity Characterization of Equine Infectious Anemia Virus Integration in the Horse Genome Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4(+) T Cells.Host Factors in Retroviral Integration and the Selection of Integration Target Sites.Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites.Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer Genomics Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes.Single-Nucleotide-Specific Targeting of the Tf1 Retrotransposon Promoted by the DNA-Binding Protein Sap1 of Schizosaccharomyces pombe.The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models.INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes

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BET proteins promote efficient murine leukemia virus integration at transcription start sites.

http://www.wikidata.org/entity/Q37031911

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on July 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

BET proteins promote efficient ...... at transcription start sites.

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BET proteins promote efficient ...... at transcription start sites.

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type

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BET proteins promote efficient ...... at transcription start sites.

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BET proteins promote efficient ...... at transcription start sites.

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BET proteins promote efficient ...... at transcription start sites.

@en

BET proteins promote efficient ...... at transcription start sites.

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PNAS.1307157110

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Proceedings of the National Academy of Sciences of the United States of America

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BET proteins promote efficient ...... at transcription start sites.

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Alison Slaughter

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Amit Sharma

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Frances Male

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Jacques J Kessl

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Matthew R Plumb

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Monica J Roth

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Nikolozi Shkriabai

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Nirav Malani

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Patrick L Green

http://www.w3.org/2001/XMLSchema#string

Ross C Larue

http://www.w3.org/2001/XMLSchema#string

P2860

Selective inhibition of BET bromodomains

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

Retroviral intasome assembly and inhibition of DNA strand transfer

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

Gene therapy for primary immunodeficiencies

Retroviral integrations in gene therapy trials

Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes

The bromodomain: a chromatin-targeting module?

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

Selective recognition of acetylated histones by bromodomain proteins visualized in living cells

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12036-12041

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scholarly article

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10.1073/PNAS.1307157110

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29

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110

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Frederic D. Bushman

Elizabeth Coward

Mamuka Kvaratskhelia

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2013-07-01T00:00:00Z

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244482674

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23818621

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3718171

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