Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia. - sprookjes - yvandenbroek - TriplyDB

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

http://www.wikidata.org/entity/Q37035173

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DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy ZNF384-related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype.Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles.An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia.EP300-ZNF384 fusion gene product up-regulates GATA3 gene expression and induces hematopoietic stem cell gene expression signature in B-cell precursor acute lymphoblastic leukemia cells.ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics.Genetic Basis of Acute Lymphoblastic Leukemia.High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia.B lymphoblastic leukemia/lymphoma: new insights into genetics, molecular aberrations, subclassification and targeted therapy.Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.Cancer-type dependent expression of CK2 transcripts.Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia.High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia.New Challenges in Targeting Signaling Pathways in Acute Lymphoblastic Leukemia by NGS Approaches: An Update.Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression.Facioscapulohumeral dystrophy: Activating an early embryonic transcriptional program in human skeletal muscle.Structural basis of DUX4/IGH-driven transactivation.New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia

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Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

http://www.wikidata.org/entity/Q37035173

description

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article scientifique

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articolo scientifico

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bilimsel makale

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scientific article published on 13 May 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

@en

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

@nl

type

label

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

@en

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

@nl

prefLabel

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

@en

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

@nl

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J.EBIOM.2016.04.038

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Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.

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Bai-Yan Wang

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Ben-Shang Li

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Bing Chen

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Cheng Cheng

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Deqing Pei

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Gang Wu

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Jian-Da Hu

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Jian-Feng Li

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Jian-Qing Mi

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Jie Kong

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P2860

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.

A method and server for predicting damaging missense mutations

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state

Patterns of somatic mutation in human cancer genomes

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

Stepwise reprogramming of B cells into macrophages.

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10.1016/J.EBIOM.2016.04.038

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