Differently phosphorylated forms of the cortactin homolog HS1 mediate distinct functions in natural killer cells
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Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cellsCell biological steps and checkpoints in accessing NK cell cytotoxicityRole of cortactin homolog HS1 in transendothelial migration of natural killer cellsTwo Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated CortactinSDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells.Immunoinhibitory adapter protein Src homology domain 3 lymphocyte protein 2 (SLy2) regulates actin dynamics and B cell spreading.Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment.Navigating barriers: the challenge of directed secretion at the natural killer cell lytic immunological synapse.The role of HLA-G in immunity and hematopoiesis.Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodiaThe identification of loci for immune traits in chickens using a genome-wide association study.Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells.The actin regulatory protein HS1 interacts with Arp2/3 and mediates efficient neutrophil chemotaxis.Human NK cell lytic granules and regulation of their exocytosisMolecular analysis of Arp2/3 complex activation in cells.Abl tyrosine kinases in T-cell signalingCoordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activationImmune pathology associated with altered actin cytoskeleton regulation.Molecular mechanisms of natural killer cell activation.The actin regulatory protein HS1 is required for antigen uptake and presentation by dendritic cells.Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity.The Arp2/3 complex binding protein HS1 is required for efficient dendritic cell random migration and force generation.Hematopoietic lineage cell-specific protein 1 immunoreactivity indicates an increased risk of poor overall survival in patients with ovarian carcinoma.How the microenvironment shapes chronic lymphocytic leukemia: the cytoskeleton connectionHematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells
P2860
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P2860
Differently phosphorylated forms of the cortactin homolog HS1 mediate distinct functions in natural killer cells
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 June 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Differently phosphorylated for ...... ctions in natural killer cells
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Differently phosphorylated for ...... tions in natural killer cells.
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type
label
Differently phosphorylated for ...... ctions in natural killer cells
@en
Differently phosphorylated for ...... tions in natural killer cells.
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prefLabel
Differently phosphorylated for ...... ctions in natural killer cells
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Differently phosphorylated for ...... tions in natural killer cells.
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P2860
P356
P1433
P1476
Differently phosphorylated for ...... ctions in natural killer cells
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P2093
Boyd Butler
Diana H Kastendieck
P2860
P304
P356
10.1038/NI.1630
P407
P577
2008-06-29T00:00:00Z