Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways. - sprookjes - yvandenbroek - TriplyDB

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

http://www.wikidata.org/entity/Q37061991

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The Janus Face of Death Receptor Signaling during Tumor Immunoediting TRAIL-mediated apoptosis in breast cancer cells cultured as 3D spheroids Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines Clinical significance of serum soluble death receptor 5 concentration in locally advanced non-small cell lung cancer patients.Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy.A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death.Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling.An added dimension to tumour TRAIL sensitivity.One-pot system for synthesis, assembly, and display of functional single-span membrane proteins on oil-water interfaces.The Deubiquitinase Inhibitor PR-619 Sensitizes Normal Human Fibroblasts to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Cell Death.Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs.Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade.Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL.Homoharringtonine, a clinically approved anti-leukemia drug, sensitizes tumor cells for TRAIL-induced necroptosis.Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism.NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis.TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells.Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML

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Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

http://www.wikidata.org/entity/Q37061991

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 04 July 2013

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

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name

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

@en

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

@nl

type

label

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

@en

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

@nl

prefLabel

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

@en

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

@nl

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Cell Death and Disease

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Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.

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A Halpin-McCormick

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A Samali

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E Szegezdi

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Bioconductor: open software development for computational biology and bioinformatics

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

Inhibition of death receptor signals by cellular FLIP

X-linked IAP is a direct inhibitor of cell-death proteases

Identification of an antiapoptotic protein complex at death receptors

Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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e702

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scholarly article

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10.1038/CDDIS.2013.214

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