SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.
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The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells.SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation.The mTOR inhibition in concurrence with ERK1/2 activation is involved in excessive autophagy induced by glycyrrhizin in hepatocellular carcinoma.Ras-ling with new therapeutic targets for metastasis.PI3K signaling in cancer: beyond AKT.SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway.JNK, p38, ERK, and SGK1 Inhibitors in Cancer.The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme.A Large-Scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells.The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression.SGK1 Inhibits Autophagy in Murine Muscle Tissue.SGK1 inhibition-induced autophagy impairs prostate cancer metastasis by reversing EMT.New Multitarget Approaches in the War Against Glioblastoma: A Mini-PerspectiveReprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors
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P2860
SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 February 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
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type
label
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@nl
prefLabel
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@nl
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P2860
P50
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SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
P2093
Agnese Barone
Cataldo Bianco
Cristina Talarico
Francesco Trapasso
Lucia D'Antona
Nicola Amodio
Nicola Perrotti
Rosario Amato
Silvia Schenone
Stefania Belviso
P2860
P304
15868-15884
P356
10.18632/ONCOTARGET.7520
P407
P577
2016-02-19T00:00:00Z