SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.

SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.

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http://www.wikidata.org/entity/Q37085905
The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells.SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation.The mTOR inhibition in concurrence with ERK1/2 activation is involved in excessive autophagy induced by glycyrrhizin in hepatocellular carcinoma.Ras-ling with new therapeutic targets for metastasis.PI3K signaling in cancer: beyond AKT.SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway.JNK, p38, ERK, and SGK1 Inhibitors in Cancer.The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme.A Large-Scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells.The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression.SGK1 Inhibits Autophagy in Murine Muscle Tissue.SGK1 inhibition-induced autophagy impairs prostate cancer metastasis by reversing EMT.New Multitarget Approaches in the War Against Glioblastoma: A Mini-PerspectiveReprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors
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SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.

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http://www.wikidata.org/entity/Q37085905
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 February 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@nl
type
label
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@nl
prefLabel
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@nl
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P2860
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P577
P5875
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P1433
P1476
SI113, a SGK1 inhibitor, poten ...... glioblastoma multiforme cells.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932