Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.
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From nose to brain: development of gonadotrophin-releasing hormone-1 neuronesCentral hypogonadotropic hypogonadism: genetic complexity of a complex diseaseUSP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental DisorderGene dosage of Otx2 is important for fertility in male mice.Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.Loss of magel2, a candidate gene for features of Prader-Willi syndrome, impairs reproductive function in mice.A role for FE65 in controlling GnRH-1 neurogenesis.Central precocious puberty that appears to be sporadic caused by paternally inherited mutations in the imprinted gene makorin ring finger 3.Using evolutionary conserved modules in gene networks as a strategy to leverage high throughput gene expression queriesAnalysis of different medulloblastoma histotypes by two-dimensional gel and MALDI-TOF.Necdin protects embryonic motoneurons from programmed cell death.Neural crest and ectodermal cells intermix in the nasal placode to give rise to GnRH-1 neurons, sensory neurons, and olfactory ensheathing cellsEnhancers of GnRH transcription embedded in an upstream gene use homeodomain proteins to specify hypothalamic expression.Prader-Willi Syndrome: Obesity due to Genomic Imprinting.Gonadotropin-releasing hormone (GnRH) neuron migration: initiation, maintenance and cessation as critical steps to ensure normal reproductive functionNetrin-1 stimulates developing GnRH neurons to extend neurites to the median eminence in a calcium- dependent mannerDeletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism.Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome.Placental protection of the fetal brain during short-term food deprivation.Mutational analysis of the necdin gene in patients with congenital isolated hypogonadotropic hypogonadism.Msx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope developmentPromotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults.New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain.Mechanism of pain generation for endometriosis-associated pelvic pain.Patterning, specification, and differentiation in the developing hypothalamus.Prader Willi Syndrome: Genetics, Metabolomics, Hormonal Function, and New Approaches to Therapy.Expression of non-coding RNA AB063319 derived from Rian gene during mouse development.Prader-Willi and Angelman SyndromeRecommendations for the investigation of animal models of Prader-Willi syndrome.Necdin shapes serotonergic development and SERT activity modulating breathing in a mouse model for Prader-Willi syndrome.Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus.Neonatal Features of The Prader-Willi Syndrome; The Case for Making The Diagnosis During The First Week of Life.
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Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 17 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Necdin, a Prader-Willi syndrom ...... ne neurons during development.
@en
Necdin, a Prader-Willi syndrom ...... ne neurons during development.
@nl
type
label
Necdin, a Prader-Willi syndrom ...... ne neurons during development.
@en
Necdin, a Prader-Willi syndrom ...... ne neurons during development.
@nl
prefLabel
Necdin, a Prader-Willi syndrom ...... ne neurons during development.
@en
Necdin, a Prader-Willi syndrom ...... ne neurons during development.
@nl
P2860
P356
P1476
Necdin, a Prader-Willi syndrom ...... one neurons during development
@en
P2093
Nichol L G Miller
Pamela L Mellon
P2860
P304
P356
10.1093/HMG/DDN344
P577
2008-10-17T00:00:00Z