Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
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Erythropoietin or darbepoetin for patients with cancerStress Response Leading to Resistance in Glioblastoma-The Need for Innovative Radiotherapy (iRT) ConceptsImaging Modalities to Assess Oxygen Status in GlioblastomaDefining normoxia, physoxia and hypoxia in tumours-implications for treatment responseHypoxia-induced modulation of apoptosis and BCL-2 family proteins in different cancer cell typesHIF1α and HIF2α independently activate SRC to promote melanoma metastasesHyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model.Modeling tumor growth and treatment response based on quantitative imaging dataNon-invasive monitoring of intra-tumor drug concentration and therapeutic response using optical spectroscopyQuantitative assessment of hypoxia subtypes in microcirculatory supply units of malignant tumors using (immuno-)fluorescence techniques.Safe Brain Tumor Resection Does not Depend on Surgery Alone - Role of Hemodynamics.Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases.Correlation of a priori DCE-MRI and (1)H-MRS data with molecular markers in neck nodal metastases: Initial analysis.Acute versus chronic hypoxia in tumors: Controversial data concerning time frames and biological consequences.Biodistribution and radiation dosimetry of the hypoxia marker 18F-HX4 in monkeys and humans determined by using whole-body PET/CTMonitoring oxygen levels in orthotopic human glioma xenograft following carbogen inhalation and chemotherapy by implantable resonator-based oximetry.Modulation of tumor hypoxia by topical formulations with vasodilators for enhancing therapy.Dynamic contrast-enhanced magnetic resonance imaging as a predictor of outcome in head-and-neck squamous cell carcinoma patients with nodal metastasesHIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironmentInfluence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1.DNA strand cleaving properties and hypoxia-selective cytotoxicity of 7-chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-dioxide.Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment.Effects of oxygen on the antigenic landscape of prostate cancer cells.Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma.Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole.The diverse and complex roles of radiation on cancer treatment: therapeutic target and genome maintenance.Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells.The twisted survivin connection to angiogenesisPharmacokinetic Analysis of (64)Cu-ATSM Dynamic PET in Human Xenograft Tumors in MiceThe Wnt/β-catenin signaling/Id2 cascade mediates the effects of hypoxia on the hierarchy of colorectal-cancer stem cellsMicroRNA-584-3p, a novel tumor suppressor and prognostic marker, reduces the migration and invasion of human glioma cells by targeting hypoxia-induced ROCK1.Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality.MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen.Blood flow responses to mild-intensity exercise in ectopic vs. orthotopic prostate tumors; dependence upon host tissue hemodynamics and vascular reactivity.A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathwayTissue pO2 of orthotopic 9L and C6 gliomas and tumor-specific response to radiotherapy and hyperoxygenation.Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis.Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours.Synthesis and Biological Evaluation of a New Nitroimidazole-99mTc-Complex for Imaging of Hypoxia in Mice Model.Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors.
P2860
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Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
@en
Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
@nl
type
label
Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
@en
Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
@nl
prefLabel
Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
@en
Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
@nl
P1433
P1476
Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.
@en
P2093
Peter Vaupel
P356
10.1634/THEONCOLOGIST.13-S3-21
P478
13 Suppl 3
P577
2008-01-01T00:00:00Z