Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. - sprookjes - yvandenbroek - TriplyDB

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

http://www.wikidata.org/entity/Q37193000

about

Calcium phosphate nanoparticles-based systems for siRNA delivery RNA-Based Vaccines in Cancer Immunotherapy The involvement of microRNAs in neurodegenerative diseases The Telomerase-Derived Anticancer Peptide Vaccine GV1001 as an Extracellular Heat Shock Protein-Mediated Cell-Penetrating Peptide Preclinical and clinical development of siRNA-based therapeutics Direct translocation as major cellular uptake for CADY self-assembling peptide-based nanoparticles Lipid-based vectors for siRNA delivery RNA therapeutics: RNAi and antisense mechanisms and clinical applications Silencing disease genes in the laboratory and the clinic DNA-aptamer targeting vimentin for tumor therapy in vivo.Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor.Structural characterization of cationic lipid-tRNA complexes.Sequence-non-specific effects of RNA interference triggers and microRNA regulators.Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells Multifunctional aptamer-miRNA conjugates for targeted cancer therapy.Oligonucleotide-based strategies to combat polyglutamine diseases.MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer.Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease.Evaluating the effect of ionic strength on duplex stability for PNA having negatively or positively charged side chains.Tumor-targeted RNA-interference: functional non-viral nanovectors.High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth.Knockdown of the sodium-dependent phosphate co-transporter 2b (NPT2b) suppresses lung tumorigenesis.Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes.Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications A molecular umbrella approach to the intracellular delivery of small interfering RNA.Anti-tumor efficacy of naked siRNAs for ERBB3 or AKT2 against lung adenocarcinoma cell xenografts.Efficient Cargo Delivery into Adult Brain Tissue Using Short Cell-Penetrating Peptides.Peptides in cancer nanomedicine: drug carriers, targeting ligands and protease substrates.siRNA Targeting the 2Apro Genomic Region Prevents Enterovirus 71 Replication In Vitro Evaluation of Therapeutic Oligonucleotides for Familial Amyloid Polyneuropathy in Patient-Derived Hepatocyte-Like Cells.Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia.U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo Comparative cellular pharmacokinetics and pharmacodynamics of siRNA delivery by SPANosomes and by cationic liposomes Antisense peptide nucleic acid-functionalized cationic nanocomplex for in vivo mRNA detection.Therapeutic potential of aptamer-siRNA conjugates for treatment of HIV-1.Use of a novel 5'-regioselective phosphitylating reagent for one-pot synthesis of nucleoside 5'-triphosphates from unprotected nucleosides.Sub-cellular temporal and spatial distribution of electrotransferred LNA/DNA oligomer Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics.Cationic shell-cross-linked knedel-like (cSCK) nanoparticles for highly efficient PNA delivery.Both helix topology and counterion distribution contribute to the more effective charge screening in dsRNA compared with dsDNA.

P2860

Q26744039-24CE2A76-F665-4D65-9711-6A087981E27E Q26776028-86D72CBC-4617-447C-8105-FA9FDA2C55D1 Q26858788-5933907F-36F4-4626-BDE9-5683F33C9468 Q28076133-C377C6A0-AFCD-4AE3-8BB8-8B61A7792B4F Q28085290-50F8C388-2494-4402-AD35-AD16412BB822 Q28477376-0B9EAE94-690C-4200-952F-C97400184D09 Q28828356-F63428DC-74F3-423C-A19A-C44465BB46BA Q28829240-DD21F36D-1BD9-4EF6-8053-E7C232462B7E Q29039090-7E94BC2D-DD3E-4BF5-9454-4EB347337120 Q30415521-4CA3740E-38A8-4092-9CFD-C45B7A2F3E4A Q30434397-5B7D5A15-D5D0-4B10-9A1D-9EA75C442C83 Q30486944-BABE7208-D522-4851-84CD-B2F59BBAD374 Q33566425-41DD16A6-5EA8-44BA-8301-A36754CBB8D0 Q33708231-E39FAF97-5912-4A79-BC16-8E0738F83C62 Q33724277-7E1E9B95-D59F-4530-ADCD-3506A4713A9E Q33791247-410BC4D2-F9F1-4D41-ABA5-EAB31328F2C7 Q34423582-9EC4D830-83D5-4EE8-BEB1-A08ADDAD557F Q34610922-9BB2ADDB-B450-4760-8271-31E9C98B1694 Q34618932-6F0ACFC1-266F-4656-927F-0620BDC54553 Q34974957-2B40C70F-8897-4DC2-A6CE-3B4366CED872 Q35024073-DA594E18-5E6C-4B54-A804-C3CC6B9E092D Q35032365-E98BE136-34BC-4820-8EB2-3659FAD7970A Q35041004-911F3CB7-D67A-4C6B-BBC4-9AEE0B238642 Q35143120-A8F7D6DB-D80C-409C-8417-375DB24F2BBD Q35555953-C6B4DA22-1AE9-4E8B-BCDD-E548639D21B4 Q35563891-742BB401-AC97-4633-8610-D019A243AD0E Q35609988-C9CC8EA8-BC60-4B76-AC45-51848285EE08 Q35783096-D0230043-FDA3-4310-B05D-9D577A2DCB3B Q35926173-9C285C05-FF1B-4702-AF97-55F3CAEA8190 Q36120100-626691AB-54E7-4DD5-AB04-BF2BA72A2EA2 Q36512593-001E3BB4-E9FC-4E5C-B710-1A846A7BD248 Q36757152-1DC643AA-6F47-4B52-BC21-C58F58280BC0 Q36788349-A499D1CE-6C56-4605-A508-01DC21547737 Q36801243-656C4B6F-3A8C-4EC8-9E46-AA8017129841 Q36839458-04B53FF7-1150-48C9-B380-92E4E555EA65 Q36847501-C16B9821-2F6D-45F3-9CD9-5E0438ECE458 Q37029450-910C61C0-AE24-4F32-8971-F910FC72B35C Q37230918-02CF6F53-38EB-494C-A23A-7340DCDC3F14 Q37236055-5F8CBBF7-4171-4031-8D15-12C1545F8F9C Q37259030-80B41964-6C02-4B55-B368-1E3EFE3EE640

P2860

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

http://www.wikidata.org/entity/Q37193000

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 16 June 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

@en

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

@nl

type

label

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

@en

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

@nl

prefLabel

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

@en

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

@nl

P1433

Q37193000-6E51B4C0-82E6-4FE1-96C2-7AE4FECDAC37

P1476

Q37193000-0D3B42D3-8110-4256-B1F5-49EB743691F6

P2093

Q37193000-1A6E6772-5B21-4986-A75A-3610FF4B1055

Q37193000-2D18D1F0-3623-4B29-8262-17287C9CDE9C

Q37193000-37B4311F-BA3C-45C2-B5D2-932742A7A116

Q37193000-4B2AABF3-DE39-4E8B-9730-4AE35360CE8A

P275

Q37193000-FDBFB703-5D13-47AE-8BE8-3E0F006E7167

P2860

Q37193000-00741AE0-09A1-4327-A4F1-9818EC1930B8

Q37193000-012B4E79-0800-492D-A175-ED9AD7B4FAF4

Q37193000-01F3C92A-98B8-4D38-81FE-2D38424E7470

Q37193000-02862368-1C3F-433C-9688-480FAB241C2D

Q37193000-04F73211-21BE-4E20-A317-831231FCEF03

Q37193000-05469B6A-D19E-4F5F-979D-99D287472CA2

Q37193000-0598E76B-5253-4190-9BC2-E16C89384158

Q37193000-05FD9D6E-7B98-40A6-834D-F723A50A670F

Q37193000-087E5D84-D172-45D8-B041-C876262CE690

Q37193000-0BD3401B-E107-4601-83D0-6A9C1B1720E5

P304

Q37193000-D4654D75-4A90-42B2-81AD-6528C01418CF

P31

Q37193000-889BD709-A7EE-4506-A19F-2C61C1A0102A

Q37193000-B759CC88-499B-45BC-8B76-6E57961CF6BC

P356

Q37193000-E71B053F-FE97-43F8-9C6A-8EB34E78D0DE

P407

Q37193000-A34546E3-6AB1-4ACF-ADBA-C12909C8596F

P433

Q37193000-024BB558-F3A9-4D70-9E57-F9D97D5D5E7F

P478

Q37193000-9220E5D6-986F-4410-B390-C4A3C38820DC

P577

Q37193000-08330DBC-4E61-466E-8459-0F2D7564F64E

Q37193000-0A3F7C29-80E8-485A-9936-94846D90F5C6

P5875

Q37193000-BCEFD91E-9519-42D7-BF04-186E4F7A824C

P698

Q37193000-48230CDB-C66E-40EF-84E8-574290F796CE

P921

Q37193000-17EAFDB4-A0D1-42CE-9137-6E08C5F0934F

Q37193000-FBC56D11-DA53-4D5B-B419-C9FBB6F7683C

P932

Q37193000-1C3200D7-08BD-49DE-9F74-F5A8CC442B8C

P356

P1433

Nucleic Acids Research

P1476

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.

@en

P2093

Hyumin Kang

http://www.w3.org/2001/XMLSchema#string

Md Rowshon Alam

http://www.w3.org/2001/XMLSchema#string

Rudy Juliano

http://www.w3.org/2001/XMLSchema#string

Vidula Dixit

http://www.w3.org/2001/XMLSchema#string

P275

Creative Commons Attribution-NonCommercial

P2860

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?

Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides

Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells

Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity

Cell signaling by receptor tyrosine kinases

Integrins: bidirectional, allosteric signaling machines

Rab proteins as membrane organizers

Silencing of microRNAs in vivo with 'antagomirs'

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

P304

4158-4171

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/NAR/GKN342

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

36

http://www.w3.org/2001/XMLSchema#string

P577

2008-06-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

2008-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5297355

http://www.w3.org/2001/XMLSchema#string

P698

18558618

http://www.w3.org/2001/XMLSchema#string

P921

regulation of gene expression

P932

2475625

http://www.w3.org/2001/XMLSchema#string