The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis
about
Targeting DNA Damage Response in the Radio(Chemo)therapy of Non-Small Cell Lung CancerTumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage ResponseDNA Damage Response and Autophagy: A Meaningful PartnershipRegulation and roles of Cdc7 kinase under replication stress.p53 Family and Cellular Stress Responses in Cancer.TAp73 promotes anti-senescence-anabolism not proliferation.A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosisTug of war between survival and death: exploring ATM function in cancer.TAp73 promotes anabolismDNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1.Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence.Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomasp63 threonine phosphorylation signals the interaction with the WW domain of the E3 ligase ItchTumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.p19(Arf) is required for the cellular response to chronic DNA damageThe Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis.Inflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis.Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.Genetic Variability as a Regulator of TLR4 and NOD Signaling in Response to Bacterial Driven DNA Damage Response (DDR) and Inflammation: Focus on the Gastrointestinal (GI) Tract.IFNγ induces oxidative stress, DNA damage and tumor cell senescence via TGFβ/SMAD signaling-dependent induction of Nox4 and suppression of ANT2.DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer.Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress.Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.MKK7 and ARF: new players in the DNA damage response scenery.Patterns of DNA damage response in intracranial germ cell tumors versus glioblastomas reflect cell of origin rather than brain environment: implications for the anti-tumor barrier concept and treatment.Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway.What a 'Ku'incidence!: parallel discoveries of a new DNA repair factor.Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation.A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
P2860
Q26743378-1B441B02-CD60-406F-B6D9-E77D15FD011BQ28070247-05CF87F0-8413-4F72-99AD-C2F429293589Q28080294-A40AD1A9-C950-43A4-9C21-34411E542CA5Q33953075-E41B1A5E-6A3B-4163-B751-A9536029C1C9Q34377287-95613BDF-A459-4DFA-8404-0FB686B6BB1CQ34774270-E129044B-2E0E-4BFD-9C09-21664468A31CQ35108867-8DCDD74F-7BBA-4D57-AF71-D7A36CF46C2FQ35134937-25DF5AB7-8271-4552-8F5C-81EE93A3A6F8Q35149652-4017D561-851D-4DD6-85FF-32B41FBF22D0Q35158045-53184223-C5A9-4E41-8919-A5670B7443E1Q35206525-EB714D4D-5D82-4A70-9DA6-11A5CA1D5CAAQ35580422-1EFE280A-693F-4F9F-8AB3-1F44ED817D8BQ35612218-432D2C9B-DDA0-4183-BA01-1B9721396FA0Q36183728-003F4730-7A95-4B30-AC51-C7FE25BD9D9CQ36191522-97F126F4-EFFE-4C2C-AD9D-C7883011BBC6Q37062834-18154307-55E3-4C6C-90C1-E200F54DE090Q37518716-1D0A1537-CB33-4194-88D5-8BA713080EC9Q37667275-96D2E870-E937-415F-9334-4D0CF4015563Q38252591-04674C9B-AEB3-442E-86EA-ED01F3532DD9Q38726846-D3F116D7-BF83-490D-AE71-18322F82F0F3Q38873861-8234B995-95B0-4722-8848-B041BB0C3F33Q38893748-6E43F52B-B6FE-45E8-B97A-B2F6E5F20015Q38936778-270EED58-156C-4AB0-AA99-F1309F18CA1DQ39669947-47B21D08-4175-46DD-8A9C-94276E111C1AQ40459014-F05B8899-08BF-4EC1-A66C-2C84E562C3EEQ41135321-B64BFEBB-2A12-4921-AA20-4CDFDBABDBCDQ41660853-96AD82B3-69DE-473E-A506-4466915CFA61Q42566225-0440E387-0A2C-42E7-AC29-69D046AF4466Q46415253-1ECC17DF-549C-4F4C-969B-4DD529D28604Q49175511-11B36CCB-78F3-4AD1-BEE0-1D7285A4E7B6Q49185499-E20F2FC7-7379-4A65-BBD2-EACEF8132BB1
P2860
The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The DNA damage checkpoint prec ...... ic stress during tumorigenesis
@en
The DNA damage checkpoint prec ...... c stress during tumorigenesis.
@nl
type
label
The DNA damage checkpoint prec ...... ic stress during tumorigenesis
@en
The DNA damage checkpoint prec ...... c stress during tumorigenesis.
@nl
prefLabel
The DNA damage checkpoint prec ...... ic stress during tumorigenesis
@en
The DNA damage checkpoint prec ...... c stress during tumorigenesis.
@nl
P2093
P2860
P50
P356
P1476
The DNA damage checkpoint prec ...... ic stress during tumorigenesis
@en
P2093
A Klinakis
A Kotsinas
B Sosa-Pineda
G Papafotiou
G Velimezi
I P Trougakos
I S Pateras
J Bartkova
K Evangelou
P2860
P2888
P304
P356
10.1038/CDD.2013.76
P577
2013-07-12T00:00:00Z