Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.
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KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfatePregnancy-specific glycoprotein 1 induces endothelial tubulogenesis through interaction with cell surface proteoglycansTargeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivityHeparan Sulfate Proteoglycans May Promote or Inhibit Cancer Progression by Interacting with Integrins and Affecting Cell MigrationSyndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and PrognosticationMolecular and clinical profiles of syndecan-1 in solid and hematological cancer for prognosis and precision medicineSyndecans play dual roles as cell adhesion receptors and docking receptorsHeparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myelomaGlycoconjugates and related molecules in human vascular endothelial cellsSpecific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migrationMMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activationExtracellular matrix as target for antitumor therapyInsights into the key roles of proteoglycans in breast cancer biology and translational medicineCharacterization of receptors for murine pregnancy specific glycoproteins 17 and 23A novel role for syndecan-3 in angiogenesisOrthotopic pancreatic tumors detected by optoacoustic tomography using Syndecan-1.Focus on molecules: syndecan-1.Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion.The niche factor syndecan-1 regulates the maintenance and proliferation of neural progenitor cells during mammalian cortical developmentThe mutual impact of syndecan-1 and its glycosaminoglycan chains--a multivariable puzzle.Integrins as "functional hubs" in the regulation of pathological angiogenesisHeparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.Functional analysis of a recombinant PIII-SVMP, GST-acocostatin; an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cellsInteraction of syndecan and alpha6beta4 integrin cytoplasmic domains: regulation of ErbB2-mediated integrin activation.Matrix regulators in neural stem cell functions.Heparan sulfate chain valency controls syndecan-4 function in cell adhesion.An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spreadDiagnostic and prognostic value of soluble syndecan-1 in pleural malignancies.SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis.Syndecan-1 in breast cancer stroma fibroblasts regulates extracellular matrix fiber organization and carcinoma cell motility.Heparan sulfate proteoglycans.Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells.Syndecan-1 regulates vascular smooth muscle cell phenotype.Tumor-derived syndecan-1 mediates distal cross-talk with bone that enhances osteoclastogenesis.Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels.Syndecan-1 and syndecan-4 are independent indicators in breast carcinomaNovel insights into the function and dynamics of extracellular matrix in liver fibrosis.The aortic ring model of angiogenesis: a quarter century of search and discovery.Syndecan-1-Induced ECM Fiber Alignment Requires Integrin αvβ3 and Syndecan-1 Ectodomain and Heparan Sulfate Chains
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P2860
Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Syndecan-1 regulates alphavbet ...... in, a novel peptide inhibitor.
@en
Syndecan-1 regulates alphavbet ...... in, a novel peptide inhibitor.
@nl
type
label
Syndecan-1 regulates alphavbet ...... in, a novel peptide inhibitor.
@en
Syndecan-1 regulates alphavbet ...... in, a novel peptide inhibitor.
@nl
prefLabel
Syndecan-1 regulates alphavbet ...... in, a novel peptide inhibitor.
@en
Syndecan-1 regulates alphavbet ...... in, a novel peptide inhibitor.
@nl
P2093
P2860
P356
P1476
Syndecan-1 regulates alphavbet ...... in, a novel peptide inhibitor.
@en
P2093
Alan C Rapraeger
Andrea R McWhorter
Brian J Ell
DeannaLee M Beauvais
P2860
P304
P356
10.1084/JEM.20081278
P407
P577
2009-03-02T00:00:00Z