Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development.
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G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosisGRK2: multiple roles beyond G protein-coupled receptor desensitizationmiR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemiasi-RNA-Mediated Silencing of ADRBK1 Gene Attenuates Breast Cancer Cell Proliferation.Multiple scaffolding functions of {beta}-arrestins in the degradation of G protein-coupled receptor kinase 2GRK5 promotes F-actin bundling and targets bundles to membrane structures to control neuronal morphogenesisG protein-coupled receptor kinases: more than just kinases and not only for GPCRsG Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progressionSmoothened is a fully competent activator of the heterotrimeric G protein G(i).Inhibition of G-protein-coupled receptor kinase 2 (GRK2) triggers the growth-promoting mitogen-activated protein kinase (MAPK) pathway.Developmental and tumoral vascularization is regulated by G protein-coupled receptor kinase 2GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewalAn essential role for Grk2 in Hedgehog signalling downstream of Smoothened.The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targetsNoncanonical Hedgehog signaling.The Hedgehog signal transduction network.Link between cancer and Alzheimer disease via oxidative stress induced by nitric oxide-dependent mitochondrial DNA overproliferation and deletionThe secret life of kinases: functions beyond catalysisGRK2 negatively regulates IGF-1R signaling pathway and cyclins' expression in HepG2 cells.Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complexGrowth inhibition of human hepatocellular carcinoma cells by overexpression of G-protein-coupled receptor kinase 2.
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Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 June 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Kinase activity-independent re ...... r zebrafish early development.
@en
Kinase activity-independent re ...... r zebrafish early development.
@nl
type
label
Kinase activity-independent re ...... r zebrafish early development.
@en
Kinase activity-independent re ...... r zebrafish early development.
@nl
prefLabel
Kinase activity-independent re ...... r zebrafish early development.
@en
Kinase activity-independent re ...... r zebrafish early development.
@nl
P2093
P2860
P356
P1476
Kinase activity-independent re ...... r zebrafish early development.
@en
P2093
P2860
P304
10183-10188
P356
10.1073/PNAS.0812105106
P407
P577
2009-06-05T00:00:00Z