Determination of intracellular unbound concentrations and subcellular localization of drugs in rat sandwich-cultured hepatocytes compared with liver tissue.
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Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat.Intracellular drug bioavailability: a new predictor of system dependent drug disposition.Prediction of Hepatic Efflux Transporter-Mediated Drug Interactions: When Is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes.Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-Cultured Hepatocytes, Mechanistic Modeling, and Simulation.Verapamil hepatic clearance in four preclinical rat models: towards activity-based scaling.Intracellular Unbound Atorvastatin Concentrations in the Presence of Metabolism and Transport.Paritaprevir and Ritonavir Liver Concentrations in Rats as Assessed by Different Liver Sampling Techniques.
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Determination of intracellular unbound concentrations and subcellular localization of drugs in rat sandwich-cultured hepatocytes compared with liver tissue.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Determination of intracellular ...... es compared with liver tissue.
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Determination of intracellular ...... es compared with liver tissue.
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type
label
Determination of intracellular ...... es compared with liver tissue.
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Determination of intracellular ...... es compared with liver tissue.
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prefLabel
Determination of intracellular ...... es compared with liver tissue.
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Determination of intracellular ...... es compared with liver tissue.
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Determination of intracellular ...... tes compared with liver tissue
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Grace Zhixia Yan
Kevin B Harris
Nathan D Pfeifer
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P304
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10.1124/DMD.113.052134
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P577
2013-08-29T00:00:00Z