Mbd2 promotes foxp3 demethylation and T-regulatory-cell function. - sprookjes - yvandenbroek - TriplyDB

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

http://www.wikidata.org/entity/Q37264378

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Emerging Molecular and Biological Functions of MBD2, a Reader of DNA Methylation Autoimmune Liver Disease Post-Liver Transplantation: A Summary and Proposed Areas for Future Research Treg functional stability and its responsiveness to the microenvironment FOXP3+ regulatory T cells and their functional regulation Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness Distinct actions of ancestral vinclozolin and juvenile stress on neural gene expression in the male rat.Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cells Transcriptional and epigenetic networks of helper T and innate lymphoid cells.Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function.A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis.Helios expression and Foxp3 TSDR methylation of IFNy+ and IFNy- Treg from kidney transplant recipients with good long-term graft function Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions.Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer.TET Methylcytosine Oxidases in T Cell and B Cell Development and Function.The elusive role of 5'-hydroxymethylcytosine.Mild hypothermia provides Treg stability.Induction of CD4(+)CD25(+)Foxp3(+) regulatory T cells by mesenchymal stem cells is associated with RUNX complex factors.The regulation of immune tolerance by FOXP3.Regulatory T cell signatures in liver transplant recipients successfully weaned from immunosuppression: Getting from here to there.Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy.miR-466a Targeting of TGF-β2 Contributes to FoxP3+ Regulatory T Cell Differentiation in a Murine Model of Allogeneic Transplantation.Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.Therapeutic Potential of Gene-Modified Regulatory T Cells: From Bench to Bedside.Histone/protein deacetylase inhibitor therapy for enhancement of Foxp3+ T-regulatory cell function posttransplantation.Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD.All-Trans Retinoic Acid Induces CD4+CD25+FOXP3+ Regulatory T Cells by Increasing FOXP3 Demethylation in Systemic Sclerosis CD4+ T Cells.STAT5 and TET2 Cooperate to Regulate FOXP3-TSDR Demethylation in CD4+ T Cells of Patients with Colorectal Cancer.

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Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

http://www.wikidata.org/entity/Q37264378

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 26 August 2013

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

@en

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

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type

label

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

@en

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

@nl

prefLabel

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

@en

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

@nl

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Molecular and Cellular Biology

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Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

@en

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Andrew D Wells

http://www.w3.org/2001/XMLSchema#string

Liqing Wang

http://www.w3.org/2001/XMLSchema#string

Rajan M Thomas

http://www.w3.org/2001/XMLSchema#string

Rongxiang Han

http://www.w3.org/2001/XMLSchema#string

Wayne W Hancock

http://www.w3.org/2001/XMLSchema#string

Yujie Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

The minimal repression domain of MBD2b overlaps with the methyl-CpG-binding domain and binds directly to Sin3A

Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development

Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation

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4106-4115

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scholarly article

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10.1128/MCB.00144-13

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20

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33

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2013-08-26T00:00:00Z

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256119588

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23979593

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3811679

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