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Recent development of ATP-competitive small molecule phosphatidylinostitol-3-kinase inhibitors as anticancer agentsHepatocellular carcinoma: Where there is unmet needGenistein Protects Genioglossus Myoblast Against Hypoxia-induced Injury through PI3K-Akt and ERK MAPK PathwaysMicroparticles Mediate the Intercellular Regulation of microRNA-503 and Proline-Rich Tyrosine Kinase 2 to Alter the Migration and Invasion Capacity of Breast Cancer Cells.Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging.Beneficial effects of hydrogen-rich saline on early burn-wound progression in rats.The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedsideAbility to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes.Suppression of Virulent Porcine Epidemic Diarrhea Virus Proliferation by the PI3K/Akt/GSK-3α/β Pathway.Phosphorylated Mammalian Target of Rapamycin p-mTOR Is a Favorable Prognostic Factor than mTOR in Gastric CancerMicroRNAs 99b-5p/100-5p Regulated by Endoplasmic Reticulum Stress are Involved in Abeta-Induced Pathologies.Advances in paediatric cancer treatmentExploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas.PTTG1 regulated by miR-146a-3p promotes bladder cancer migration, invasion, metastasis and growth.Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.Mst1 regulates glioma cell proliferation via the AKT/mTOR signaling pathway.Conventional chemotherapy and perspectives for molecular-based oncological treatment in pediatric hemispheric low-grade gliomas.Enhanced protection against renal ischemia-reperfusion injury with combined melatonin and exendin-4 in a rodent model.Vertical inhibition of the PI3K/Akt/mTOR pathway is synergistic in breast cancer.Beneficial effects of extracts from Lucilia sericata maggots on burn wounds in rats.Molecular Basis of Pediatric Brain Tumors.Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway.Tl(I) and Tl(III) alter the expression of EGF-dependent signals and cyclins required for pheochromocytoma (PC12) cell-cycle resumption and progression.Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.p-Akt and its relationship with clinicopathological features and survival in oral squamous cell carcinoma: an immunohistochemical study.Genetic code expansion and live cell imaging reveal that Thr308 phosphorylation is irreplaceable and sufficient for Akt1 activity.A new meroterpenoid functions as an anti-tumor agent in hepatoma cells by downregulating mTOR activation and inhibiting EMT
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 August 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting the PI3-kinase/Akt/mTOR signaling pathway.
@en
Targeting the PI3-kinase/Akt/mTOR signaling pathway.
@nl
type
label
Targeting the PI3-kinase/Akt/mTOR signaling pathway.
@en
Targeting the PI3-kinase/Akt/mTOR signaling pathway.
@nl
prefLabel
Targeting the PI3-kinase/Akt/mTOR signaling pathway.
@en
Targeting the PI3-kinase/Akt/mTOR signaling pathway.
@nl
P2093
P2860
P1476
Targeting the PI3-kinase/Akt/mTOR signaling pathway.
@en
P2093
Argun Akcakanat
Ashley M Holder
Burhan Hassan
P2860
P304
P356
10.1016/J.SOC.2013.06.008
P577
2013-08-06T00:00:00Z